UVR and RPE – The Good, the Bad and the degenerate Macula

IF 18.6 1区医学 Q1 OPHTHALMOLOGY

Progress in Retinal and Eye Research Pub Date : 2023-12-20 DOI:10.1016/j.preteyeres.2023.101233

Graham Anderson , Shyamanga Borooah , Roly Megaw , Pierre Bagnaninchi , Richard Weller , Andrew McLeod FRSB , Baljean Dhillon

引用次数: 0

Abstract

Ultraviolet Radiation (UVR) has a well-established causative influence within the aetiology of conditions of the skin and the anterior segment of the eye. However, a grounded assessment of the role of UVR within conditions of the retina has been hampered by a historical lack of quantitative, and spectrally resolved, assessment of how UVR impacts upon the retina in terms congruent with contemporary theories of ageing.

In this review, we sought to summarise the key findings of research investigating the connection between UVR exposure in retinal cytopathology while identifying necessary avenues for future research which can deliver a deeper understanding of UVR's place within the retinal risk landscape.

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紫外线辐射率和 RPE - 黄斑的好坏与退化

紫外线辐射（UVR）对皮肤和眼球前段的病因具有公认的致病影响。在这篇综述中，我们试图总结研究紫外线照射与视网膜细胞病理学之间联系的主要发现，同时确定未来研究的必要途径，以便更深入地了解紫外线在视网膜风险中的地位。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Progress in Retinal and Eye Research 医学-眼科学

CiteScore

34.10

自引率

5.10%

发文量

期刊介绍： Progress in Retinal and Eye Research is a Reviews-only journal. By invitation, leading experts write on basic and clinical aspects of the eye in a style appealing to molecular biologists, neuroscientists and physiologists, as well as to vision researchers and ophthalmologists. The journal covers all aspects of eye research, including topics pertaining to the retina and pigment epithelial layer, cornea, tears, lacrimal glands, aqueous humour, iris, ciliary body, trabeculum, lens, vitreous humour and diseases such as dry-eye, inflammation, keratoconus, corneal dystrophy, glaucoma and cataract.