Efficacy of transvenous embolization of CSF-venous fistula in spontaneous intracranial hypotension: Case-series.

IF 1.5 4区医学 Q4 CLINICAL NEUROLOGY

Interventional Neuroradiology Pub Date : 2023-12-21 DOI:10.1177/15910199231221449

Nathaniel R Ellens, Derrek Schartz, Rahim Ismail, Alex Kessler, Shehenaz Ellika, Sajal Medha K Akkipeddi, Redi Rahmani, Matthew T Bender

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引用次数: 0

Abstract

Background: Spontaneous intracranial hypotension is a debilitating neurological condition which can be caused by a cerebrospinal fluid-venous fistula. Transvenous embolization is a promising technique to provide minimally invasive yet durable treatment.

Methods: A retrospective single-center case series was performed on all patients who underwent transvenous embolization of a cerebrospinal fluid (CSF)-venous fistula. Clinical and radiographic parameters, including Bern score, were reported preoperatively and at 3-month follow-up.

Results: Six patients underwent embolization of a CSF-venous fistula. All fistulae were located in the thoracic spine and technical success was achieved in all cases. Three patients had symptom resolution, two had significant improvement, and one had stable symptoms on follow-up. The mean Bern score was 6.83 (SD = 1.47) preoperatively and 1.83 (SD = 1.64) postoperatively with a mean improvement in Bern score of 5.0 (SD = 1.9, p = 0.0013).

Conclusions: CSF-venous fistulas are an increasingly recognized clinical entity which may be treated with transvenous embolization. This case series serves to further validate this technique and suggests it can be performed with similar outcomes in lower volume centers.

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经静脉栓塞 CSF-静脉瘘对自发性颅内低血压的疗效：病例系列。

背景：自发性颅内低血压是一种使人衰弱的神经系统疾病，可由脑脊液-静脉瘘引起。经静脉栓塞是一种很有前景的微创而持久的治疗技术：方法：对所有接受经静脉栓塞治疗脑脊液-静脉瘘的患者进行了回顾性单中心病例系列研究。结果：6 例患者接受了栓塞术，其中 1 例患者的栓塞效果良好，1 例患者的栓塞效果不佳：结果：六名患者接受了脑脊液-静脉瘘栓塞术。所有瘘管都位于胸椎，所有病例都取得了技术上的成功。三名患者症状缓解，两名患者症状明显好转，一名患者随访时症状稳定。术前 Bern 评分平均为 6.83（SD = 1.47），术后为 1.83（SD = 1.64），Bern 评分平均提高了 5.0（SD = 1.9，P = 0.0013）：结论：脑脊液-静脉瘘是一种日益被认可的临床实体，可通过经静脉栓塞治疗。本系列病例进一步验证了这一技术，并表明在手术量较少的中心也能取得类似的疗效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Interventional Neuroradiology CLINICAL NEUROLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

CiteScore

3.60

自引率

11.80%

发文量

192

审稿时长

6-12 weeks

期刊介绍： Interventional Neuroradiology (INR) is a peer-reviewed clinical practice journal documenting the current state of interventional neuroradiology worldwide. INR publishes original clinical observations, descriptions of new techniques or procedures, case reports, and articles on the ethical and social aspects of related health care. Original research published in INR is related to the practice of interventional neuroradiology...