Ethnobotany and phytochemistry of plants used to treat musculoskeletal disorders among Skaw Karen, Thailand.

IF 3.9 3区 医学 Q1 MEDICAL LABORATORY TECHNOLOGY
Pharmaceutical Biology Pub Date : 2024-12-01 Epub Date: 2023-12-22 DOI:10.1080/13880209.2023.2292261
Rapeeporn Kantasrila, Hataichanok Pandith, Henrik Balslev, Prasit Wangpakapattanawong, Prateep Panyadee, Angkhana Inta
{"title":"Ethnobotany and phytochemistry of plants used to treat musculoskeletal disorders among Skaw Karen, Thailand.","authors":"Rapeeporn Kantasrila, Hataichanok Pandith, Henrik Balslev, Prasit Wangpakapattanawong, Prateep Panyadee, Angkhana Inta","doi":"10.1080/13880209.2023.2292261","DOIUrl":null,"url":null,"abstract":"<p><strong>Context: </strong>Musculoskeletal system disorders (MSD) are prevalent around the world affecting the health of people, especially farmers who work hard in the field. Karen farmers use many medicinal plants to treat MSD.</p><p><strong>Objective: </strong>This study collects traditional plant-based remedies used by the Skaw Karen to treat MSD and evaluates their active phytochemical compounds.</p><p><strong>Materials and methods: </strong>The ethnobotanical study was conducted in six Karen villages in Chiang Mai province using semi-structured interviews were of 120 informants. The data were analyzed using ethnobotanical indices including use values (UV), choice value (CV), and informant consensus factor (ICF). Consequently, the 20 most important species, according to the indices, were selected for phytochemical analysis using LC-MS/MS.</p><p><strong>Results: </strong>A total of 3731 use reports were obtained for 139 species used in MSD treatment. The most common ailments treated with those plants were muscular pain. A total of 172 high-potential active compounds for MSD treatment were identified. Most of them were flavonoids, terpenoids, alkaloids, and steroids. The prevalent phytochemical compounds related to treat MSD were 9-hydroxycalabaxanthone, dihydrovaltrate, morroniside, isoacteoside, lithocholic acid, pomiferin, cucurbitacin E, leonuriside A, liriodendrin, and physalin E. <i>Sambucus javanica</i> Reinw. ex Blume (Adoxaceae), <i>Betula alnoides</i> Buch.-Ham. ex D.Don (Betulaceae), <i>Blumea balsamifera</i> (L.) DC. (Asteraceae), <i>Plantago major</i> L. (Plantaginaceae) and <i>Flacourtia jangomas</i> (Lour.) Raeusch. (Salicaceae) all had high ethnobotanical index values and many active compounds.</p><p><strong>Discussion and conclusions: </strong>This study provides valuable information, demonstrating low-cost medicine plants that are locally available. It is a choice of treatment for people living in remote areas.</p>","PeriodicalId":19942,"journal":{"name":"Pharmaceutical Biology","volume":"62 1","pages":"62-104"},"PeriodicalIF":3.9000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10763916/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmaceutical Biology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/13880209.2023.2292261","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/12/22 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Context: Musculoskeletal system disorders (MSD) are prevalent around the world affecting the health of people, especially farmers who work hard in the field. Karen farmers use many medicinal plants to treat MSD.

Objective: This study collects traditional plant-based remedies used by the Skaw Karen to treat MSD and evaluates their active phytochemical compounds.

Materials and methods: The ethnobotanical study was conducted in six Karen villages in Chiang Mai province using semi-structured interviews were of 120 informants. The data were analyzed using ethnobotanical indices including use values (UV), choice value (CV), and informant consensus factor (ICF). Consequently, the 20 most important species, according to the indices, were selected for phytochemical analysis using LC-MS/MS.

Results: A total of 3731 use reports were obtained for 139 species used in MSD treatment. The most common ailments treated with those plants were muscular pain. A total of 172 high-potential active compounds for MSD treatment were identified. Most of them were flavonoids, terpenoids, alkaloids, and steroids. The prevalent phytochemical compounds related to treat MSD were 9-hydroxycalabaxanthone, dihydrovaltrate, morroniside, isoacteoside, lithocholic acid, pomiferin, cucurbitacin E, leonuriside A, liriodendrin, and physalin E. Sambucus javanica Reinw. ex Blume (Adoxaceae), Betula alnoides Buch.-Ham. ex D.Don (Betulaceae), Blumea balsamifera (L.) DC. (Asteraceae), Plantago major L. (Plantaginaceae) and Flacourtia jangomas (Lour.) Raeusch. (Salicaceae) all had high ethnobotanical index values and many active compounds.

Discussion and conclusions: This study provides valuable information, demonstrating low-cost medicine plants that are locally available. It is a choice of treatment for people living in remote areas.

泰国 Skaw Karen 族用于治疗肌肉骨骼疾病的植物的民族植物学和植物化学。
背景:肌肉骨骼系统疾病(MSD)在世界各地普遍存在,影响着人们的健康,尤其是在田间辛勤劳作的农民。克伦族农民使用许多药用植物来治疗肌肉骨骼系统疾病:本研究收集了 Skaw 克伦族用于治疗多发性硬化症的传统植物疗法,并对其活性植物化学成分进行了评估:这项民族植物学研究在清迈府的六个克伦族村落进行,采用半结构式访谈法,访问了 120 名信息提供者。数据采用民族植物学指数进行分析,包括使用价值(UV)、选择价值(CV)和信息提供者共识因子(ICF)。根据这些指数,选出了 20 种最重要的物种,利用 LC-MS/MS 进行植物化学分析:结果:共获得 3731 份用于 MSD 治疗的 139 种植物的使用报告。这些植物治疗的最常见疾病是肌肉疼痛。共鉴定出 172 种治疗 MSD 的高潜力活性化合物。其中大部分是黄酮类、萜类、生物碱和类固醇。与治疗 MSD 相关的植物化学物质主要有 9-羟基卡拉巴仙酮、二氢缬氨酸、吗罗尼苷、异内酯苷、石胆酸、绒毛素、葫芦素 E、leonuriside A、ligiodendrin 和 physalin E。exD.Don(桦木科)、Blumea balsamifera (L.) DC.(菊科)、大车前子 L.(车前子科)和黄花菜 Flacourtia jangomas (Lour.) Raeusch.(讨论与结论:这项研究提供了宝贵的信息,展示了当地可获得的低成本药用植物。对于生活在偏远地区的人们来说,这是一种治疗选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Pharmaceutical Biology
Pharmaceutical Biology 医学-药学
CiteScore
6.70
自引率
2.60%
发文量
191
审稿时长
1 months
期刊介绍: Pharmaceutical Biology will publish manuscripts describing the discovery, methods for discovery, description, analysis characterization, and production/isolation (including sources and surveys) of biologically-active chemicals or other substances, drugs, pharmaceutical products, or preparations utilized in systems of traditional medicine. Topics may generally encompass any facet of natural product research related to pharmaceutical biology. Papers dealing with agents or topics related to natural product drugs are also appropriate (e.g., semi-synthetic derivatives). Manuscripts will be published as reviews, perspectives, regular research articles, and short communications. The primary criteria for acceptance and publication are scientific rigor and potential to advance the field.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信