Host-related indexes in head and neck cancer.

IF 1.9 4区医学 Q2 OTORHINOLARYNGOLOGY

Current Opinion in Otolaryngology & Head and Neck Surgery Pub Date : 2024-04-01 Epub Date: 2023-12-01 DOI:10.1097/MOO.0000000000000954

Cristina Valero, Xavier León, Miquel Quer

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引用次数: 0

Abstract

Purpose of review: Peripheral blood host-related indexes have been widely studied in cancer patients. Several authors have shown the prognostic capacity of these indexes in head and neck cancer. Therefore, there has been an increasing interest in this topic recently.

Recent findings: The main variables analyzed and used to create these host-related indexes are peripheral blood leukocytes - including neutrophils, monocytes and lymphocytes - albumin and hemoglobin levels. Other factors with proven prognostic capacity in some studies are: platelets, C-reactive protein, and BMI. Among all the combined indexes, the neutrophil-to-lymphocyte ratio has been the most accepted and used worldwide. Nonetheless, there are other indexes which group multiple of these factors that have shown better prognostic capacity, and are promising in the near future.

Summary: Host-related indexes are ideal biomarkers to be used on our daily-basis. There is enough evidence to start considering them when assessing patients with head and neck cancer.

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头颈癌的宿主相关指数。

综述目的：外周血宿主相关指数已在癌症患者中得到广泛研究。一些学者已经证明了这些指标在头颈部癌症中的预后能力。因此，近来人们对这一课题的兴趣与日俱增：最近的研究结果：分析和用于创建这些宿主相关指数的主要变量是外周血白细胞（包括中性粒细胞、单核细胞和淋巴细胞）、白蛋白和血红蛋白水平。在一些研究中被证实具有预后能力的其他因素包括：血小板、C 反应蛋白和体重指数。在所有的综合指标中，中性粒细胞与淋巴细胞的比值是全世界公认和使用最多的。小结：宿主相关指标是我们日常使用的理想生物标志物。有足够的证据表明，在评估头颈部癌症患者时可以开始考虑这些指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Otolaryngology & Head and Neck Surgery OTORHINOLARYNGOLOGY-

CiteScore

2.90

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Otolaryngology & Head and Neck Surgery is a bimonthly publication offering a unique and wide ranging perspective on the key developments in the field. Each issue features hand-picked review articles from our team of expert editors. With eleven disciplines published across the year – including maxillofacial surgery, head and neck oncology and speech therapy and rehabilitation – every issue also contains annotated references detailing the merits of the most important papers.