Retrospective Analysis of Lipid-Lowering and Antiplatelet Therapy Regimen by Clinical Decision Support Service Based on Real-World Data from Electronic Medical Records "Intellect 3 Study".

IF 0.5 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Kardiologiya Pub Date : 2023-12-05 DOI:10.18087/cardio.2023.11.n2555

K S Benimetskaya, S I Provatorov, M V Ezhov, Y S Krivosheev, A D Gavrilko, A E Uranov, I L Mikheenko, E A Kovalev, A V Ponomarenko, A M Shangina, Yu E Efremova, T E Kolmakova, M A Matveeva, Yu A Dolgusheva, I A Alekseeva, A K Osokina, D N Nozadze, I V Atyunina, F N Paleev, M A Meshkova, Yu A Sharapova, D V Losik

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引用次数: 0

Abstract

Aim To evaluate prescription of lipid-lowering and antithrombotic therapy in clinical practice and to compare differences in recommendations using the clinical decision support service (CDSS).Material and methods Electronic medical records (EMR) of 300 patients from the Chazov National Medical Research Center of Cardiology, as well as from medical organizations controlled by the Department of Health of the Lipetsk Region and the Ministry of Health of the Voronezh Region, were analyzed for the period of August - December 2022, during the pilot implementation of CDSS. Retrospective information about the prescription of lipid-lowering and antithrombotic therapy from the EMR was compared with the CDSS guidelines under the expert supervision based on digitized clinical and laboratory profiles of patients. The study primary endpoint was a change in the initially prescribed lipid-lowering and / or antithrombotic therapy as per CDSS guidelines.Results Overall 292 patients were included in the final analysis; 46 (15.7 %) were from the primary prevention group and 246 (84.3 %) from the secondary prevention group. In group 1, the lipid-lowering therapy recommended by the CDSS differed by 50 % (p<0.001) from the baseline therapy recorded in the EMR. In the secondary prevention group, 78.9 % (p<0.001) differences were found in the lipid-lowering therapy recommended in the CDSS guidelines compared to the prescriptions in the EMR. In 76.8 % (p<0.001) of patients, antithrombotic therapy was significantly different from the baseline therapy in the EMR.Conclusion The use of CDSS may improve the practice of choosing lipid-lowering and antithrombotic therapy for prevention of cardiovascular complications.

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基于电子病历真实数据的临床决策支持服务对降脂和抗血小板治疗方案的回顾性分析 "Intellect 3 研究"。

材料与方法在试点实施临床决策支持服务（CDSS）期间，对查佐夫国家心脏病学医学研究中心以及利佩茨克州卫生局和沃罗涅日州卫生部下属医疗机构的300名患者在2022年8月至12月期间的电子病历（EMR）进行了分析。在专家的监督下，根据患者的数字化临床和实验室资料，将EMR中有关降血脂和抗血栓治疗处方的回顾性信息与CDSS指南进行了比较。研究的主要终点是根据 CDSS 指南最初开出的降脂和/或抗血栓治疗处方的变化。结果共有 292 名患者被纳入最终分析，其中 46 人（15.7%）来自一级预防组，246 人（84.3%）来自二级预防组。在第一组中，CDSS推荐的降脂疗法与EMR记录的基线疗法相差50%（p<0.001）。在二级预防组中，CDSS指南推荐的降脂疗法与EMR中的处方相差78.9%（p<0.001）。76.8%（p<0.001）的患者的抗血栓治疗与 EMR 中的基线治疗存在显著差异。

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来源期刊

Kardiologiya 医学-心血管系统

CiteScore

1.70

自引率

20.00%

发文量

审稿时长

3-8 weeks

期刊介绍： “Kardiologiya” (Cardiology) is a monthly scientific, peer-reviewed journal committed to both basic cardiovascular medicine and practical aspects of cardiology. As the leader in its field, “Kardiologiya” provides original coverage of recent progress in cardiovascular medicine. We publish state-of-the-art articles integrating clinical and research activities in the fields of basic cardiovascular science and clinical cardiology, with a focus on emerging issues in cardiovascular disease. Our target audience spans a diversity of health care professionals and medical researchers working in cardiovascular medicine and related fields. The principal language of the Journal is Russian, an additional language – English (title, authors’ information, abstract, keywords). “Kardiologiya” is a peer-reviewed scientific journal. All articles are reviewed by scientists, who gained high international prestige in cardiovascular science and clinical cardiology. The Journal is currently cited and indexed in major Abstracting & Indexing databases: Web of Science, Medline and Scopus. The Journal''s primary objectives Contribute to raising the professional level of medical researchers, physicians and academic teachers. Present the results of current research and clinical observations, explore the effectiveness of drug and non-drug treatments of heart disease, inform about new diagnostic techniques; discuss current trends and new advancements in clinical cardiology, contribute to continuing medical education, inform readers about results of Russian and international scientific forums; Further improve the general quality of reviewing and editing of manuscripts submitted for publication; Provide the widest possible dissemination of the published articles, among the global scientific community; Extend distribution and indexing of scientific publications in major Abstracting & Indexing databases.