Importance and use of corneal biomechanics and its diagnostic utility.

Arturo Ramirez-Miranda, Simran Mangwani-Mordani, José Y Arteaga-Rivera, Renato Ambrosio, Alejandro Navas, Enrique O Graue-Hernandez, Jorge E Valdez-Garcia
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Abstract

The study of corneal biomechanics has become relevant in recent years due to its possible applications in the diagnosis, management, and treatment of various diseases such as glaucoma, keratorefractive surgery and different corneal diseases. The clinical biomechanical investigation has become of great importance in the setting of refractive surgery to identify patients at higher risk of developing iatrogenic ectasia. This review focuses on two of the technologies available for clinical use, the Ocular Response Analyzer (Reichert Ophthalmic Instruments, Buffalo, NY, USA) and the Corvis ST (Oculus Optikgergäte GmbH, Wetzlar, Germany). Both are non-contact tonometers that provided a clinical evaluation of corneal biomechanics. The fundamentals and main parameters of each device are described, as well as their use in eye surgery and the corneal biomechanical behavior in eye diseases. Finally, we will discuss the more recent Brillouin microscopy biomechanical analysis, and the integration Scheimpflug-based corneal tomography and biomechanical data with artificial intelligence to increase accuracy to detect risk of ectasia.

角膜生物力学的重要性和用途及其诊断作用。
近年来,角膜生物力学的研究变得越来越重要,因为它可以应用于各种疾病的诊断、管理和治疗,如青光眼、角膜屈光手术和各种角膜疾病。在屈光手术中,临床生物力学研究对识别发生先天性角膜异位症风险较高的患者具有重要意义。本综述重点介绍两种可用于临床的技术,即眼球反应分析仪(Reichert 眼科仪器公司,美国纽约州布法罗市)和 Corvis ST(Oculus Optikgergäte GmbH 公司,德国韦茨拉尔市)。这两种仪器都是非接触式眼压计,可对角膜生物力学进行临床评估。我们将介绍每种设备的基本原理和主要参数,以及它们在眼科手术中的应用和眼科疾病中的角膜生物力学行为。最后,我们将讨论最新的布里渊显微镜生物力学分析,以及基于 Scheimpflug 的角膜层析成像和生物力学数据与人工智能的整合,以提高检测异位风险的准确性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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