[Increase in severe acute respiratory infections in children during the last phase of the COVID-19 pandemic].

IF 1.9 4区 医学 Q4 MICROBIOLOGY
Revista Espanola De Quimioterapia Pub Date : 2024-02-01 Epub Date: 2023-12-20 DOI:10.37201/req/074.2023
L Bermúdez-Barrezueta, M Brezmes Raposo, M Brezmes Raposo, M Gutiérrez Jimeno, E Rodríguez Merino, M Pino-Velázquez, C Fernández García-Abril, S Rojo Rello, J M Eiros Bouza, M A Pino-Vázquez
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引用次数: 0

Abstract

Objective: The COVID-19 pandemic has caused a variation in the circulation of respiratory pathogens. Our aim was to analyze the epidemiology of severe acute respiratory infections (SARI) in children during 3 years of the COVID-19 pandemic, in comparison with a previous period.

Methods: An observational study was conducted in a tertiary hospital in Spain, which analyzed the frequency and characteristics of patients admitted for SARI in the Pediatric Intensive Care Unit (PICU) during the COVID-19 pandemic (1 March 2020 to 28 February 2023), compared to pre-pandemic period (1 March 2017 to 29 February 2020).

Results: A total of 268 patients were included (59.6% males). The median age was 9.6 months (IQR 1.7 - 37). In the pre-pandemic period, there were 126 admissions with an average of 42 admissions/year. During the pandemic, there were 142 admissions, observing a significant reduction in admissions in the first year (12 admissions/year), in contrast to 82 admissions during the third year, which represented an increase of 95% compared to the average of admissions/year in pre-pandemic. In addition, in the last year there was evidence of an increase in viral coinfections in relation to pre-pandemic period (54.9% vs 39.7%; p=0.032). There were no differences in length of hospital stay or PICU stay.

Conclusions: During the last year, coinciding with low rates of hospitalization for COVID in Spain, we observed a notable increase in admissions to the PICU for SARI. Probably, the prolonged period of low exposure to pathogens due to the measures adopted during the pandemic might have caused a decrease in population immunity with a rise in severe respiratory infections.

[COVID-19大流行最后阶段儿童严重急性呼吸道感染增加]。
目的:COVID-19 大流行导致呼吸道病原体的流通发生变化。我们的目的是分析 COVID-19 大流行 3 年间儿童严重急性呼吸道感染(SARI)的流行病学情况,并与之前的情况进行比较:西班牙一家三甲医院开展了一项观察性研究,分析了COVID-19大流行期间(2020年3月1日至2023年2月28日)与大流行前(2017年3月1日至2020年2月29日)相比,儿科重症监护室(PICU)收治的SARI患者的频率和特征:共纳入 268 名患者(59.6% 为男性)。中位年龄为 9.6 个月(IQR 1.7 - 37)。在大流行前,共有 126 人入院,平均每年 42 人入院。大流行期间,入院人数为 142 人,观察到第一年的入院人数显著减少(12 人/年),而第三年的入院人数为 82 人,与大流行前的平均入院人数/年相比增加了 95%。此外,有证据表明,与大流行前相比,去年的病毒合并感染率有所上升(54.9% 对 39.7%;P=0.032)。住院时间和重症监护病房的住院时间没有差异:结论:去年,在西班牙因 COVID 住院率较低的同时,我们发现因 SARI 而入住 PICU 的人数明显增加。可能是由于大流行期间采取的措施导致病原体接触率长期处于较低水平,从而导致人群免疫力下降,严重呼吸道感染病例增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.90
自引率
10.50%
发文量
146
审稿时长
>12 weeks
期刊介绍: The official journal of the Sociedad Española de Quimioterapia (Spanish Society of Chemotherapy), publishes articles that further knowledge and advance the science and application of antimicrobial chemotherapy with antibiotics and antifungal, antiviral and antiprotozoal agents primarily in human medicine. Authors sign an exclusive license agreement, where authors have copyright but license exclusive rights in their article to the Publisher. All manuscripts are free open access. Revista Española de Quimioterapia includes the following sections: reviews, original articles, brierf reports, letters, and consensus documents.
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