Targeting GABA receptors with chalcone derivative compounds, what is the evidence?
IF 4.6
2区 医学
Q1 PHARMACOLOGY & PHARMACY
引用次数: 0
Abstract
In medicinal chemistry, privileged structures have been frequently exploited as a successful template for drug discovery. Common simple scaffolds like chalcone are present in a wide range of natura...用查尔酮衍生物化合物靶向 GABA 受体，证据何在？
在药物化学中，特权结构经常被用作药物发现的成功模板。常见的简单支架，如查耳酮，广泛存在于自然界的各种化合物中。
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来源期刊
CiteScore
8.90
自引率
1.70%
发文量
58
审稿时长
3 months
期刊介绍：
The journal evaluates molecules, signalling pathways, receptors and other therapeutic targets and their potential as candidates for drug development. Articles in this journal focus on the molecular level and early preclinical studies. Articles should not include clinical information including specific drugs and clinical trials.
The Editors welcome:
Reviews covering novel disease targets at the molecular level and information on early preclinical studies and their implications for future drug development.
Articles should not include clinical information including specific drugs and clinical trials.
Original research papers reporting results of target selection and validation studies and basic mechanism of action studies for investigative and marketed drugs.
The audience consists of scientists, managers and decision makers in the pharmaceutical industry, academic researchers working in the field of molecular medicine and others closely involved in R&D.
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