Occupational exposure to vapors, gasses, dusts, and fumes in relation to causes of death during 24 years in Helsinki, Finland

IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Juuso Jalasto, Ritva Luukkonen, Ari Lindqvist, Arnulf Langhammer, Hannu Kankaanranta, Helena Backman, Eva Rönmark, Anssi Sovijärvi, Päivi Piirilä, Paula Kauppi
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Abstract

Purpose

Environmental particulate matter (PM) exposure has been shown to cause excess all-cause and disease-specific mortality. Our aim was to compare disease-specific mortality by estimated occupational exposure to vapors, gasses, dusts, and fumes (VGDF).

Methods

The data source is the Helsinki part of the population-based FinEsS study on chronic obstructive pulmonary diseases including information on age, education level, main occupation, sex, and tobacco smoking combined with death registry information. We compared estimated VGDF exposure to mortality using adjusted competing-risks regression for disease-specific survival analysis for a 24-year follow-up.

Results

Compared to the no-exposure group, the high occupational VGDF exposure group had sub-hazard ratios (sHR) of 1.7 (95% CI 1.3–2.2) for all cardiovascular-related and sHR 2.1 (1.5–3.9) for just coronary artery-related mortality. It also had sHR 1.7 (1.0–2.8) for Alzheimer’s or vascular dementia-related mortality and sHR 1.7(1.2–2.4) for all respiratory disease-related mortality.

Conclusion

Long-term occupational exposure to VGDF increased the hazard of mortality- to cardiovascular-, respiratory-, and dementia-related causes. This emphasizes the need for minimizing occupational long-term respiratory exposure to dust, gasses, and fumes.

Abstract Image

芬兰赫尔辛基 24 年间与蒸汽、气体、粉尘和烟雾的职业接触与死亡原因的关系
目的环境颗粒物(PM)暴露已被证明会导致超常的全因死亡率和特定疾病死亡率。我们的目的是根据蒸汽、气体、粉尘和烟雾(VGDF)的估计职业暴露量来比较疾病特异性死亡率。方法数据来源于基于人群的慢性阻塞性肺病 FinEsS 研究的赫尔辛基部分,包括年龄、教育水平、主要职业、性别和吸烟等信息以及死亡登记信息。结果与未暴露组相比,高职业 VGDF 暴露组所有心血管相关死亡率的次危险比 (sHR) 为 1.7 (95% CI 1.3-2.2),仅冠状动脉相关死亡率的次危险比 (sHR) 为 2.1 (1.5-3.9)。结论 长期职业暴露于 VGDF 会增加心血管、呼吸系统和痴呆相关原因的死亡率。这强调了尽量减少职业性长期呼吸接触粉尘、气体和烟雾的必要性。
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来源期刊
International Archives of Occupational and Environmental Health
International Archives of Occupational and Environmental Health 医学-公共卫生、环境卫生与职业卫生
CiteScore
5.60
自引率
6.70%
发文量
127
审稿时长
3 months
期刊介绍: International Archives of Occupational and Environmental Health publishes Editorials, Review Articles, Original Articles, and Letters to the Editor. It welcomes any manuscripts dealing with occupational or ambient environmental problems, with a special interest in research at the interface of occupational health and clinical medicine. The scope ranges from Biological Monitoring to Dermatology, from Fibers and Dust to Human Toxicology, from Nanomaterials and Ultra-fine Dust to Night- and Shift Work, from Psycho-mental Distress and Burnout to Vibrations. A complete list of topics can be found on the right-hand side under For authors and editors. In addition, all papers should be based on present-day standards and relate to: -Clinical and epidemiological studies on morbidity and mortality -Clinical epidemiological studies on the parameters relevant to the estimation of health risks -Human experimental studies on environmental health effects. Animal experiments are only acceptable if relevant to pathogenic aspects. -Methods for studying the topics mentioned above.
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