Embryonal and pineal tumours

IF 1.2 4区 医学 Q4 CELL BIOLOGY
Cytopathology Pub Date : 2023-12-15 DOI:10.1111/cyt.13350
Joseph Reznicek, Nima Sharifai, Pouya Jamshidi, Nitin Wadhwani, Jared T. Ahrendsen
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引用次数: 0

Abstract

Embryonal and pineal tumours represent a diverse group of central nervous system (CNS) neoplasms. While many of the small round blue cell tumours that make up the embryonal neoplasms share similar histologic qualities, there are several morphologic and cytologic characteristics that are useful in distinguishing different tumour types. Similarly, pineal parenchymal tumours represent clinically diverse tumours, ranging from benign to overtly malignant. The most recent iteration of the World Health Organization Classification of CNS Tumours expanded greatly on the significance of molecular alterations in brain tumour diagnostics. In this article, we summarize the salient cytologic and histologic features of CNS embryonal and pineal tumours, and highlight diagnostically relevant molecular alterations within each tumour type.

Abstract Image

胚胎和松果体肿瘤
胚胎瘤和松果体瘤是中枢神经系统(CNS)肿瘤中的一种。虽然构成胚胎性肿瘤的许多小圆形蓝细胞瘤具有相似的组织学特征,但有几种形态学和细胞学特征有助于区分不同的肿瘤类型。同样,松果体实质肿瘤在临床上也是多种多样的,从良性到明显恶性不等。世界卫生组织中枢神经系统肿瘤分类的最新版本大大扩展了分子改变在脑肿瘤诊断中的意义。在本文中,我们总结了中枢神经系统胚胎瘤和松果体瘤的细胞学和组织学特征,并重点介绍了每种肿瘤类型中与诊断相关的分子改变。
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来源期刊
Cytopathology
Cytopathology 生物-病理学
CiteScore
2.30
自引率
15.40%
发文量
107
审稿时长
6-12 weeks
期刊介绍: The aim of Cytopathology is to publish articles relating to those aspects of cytology which will increase our knowledge and understanding of the aetiology, diagnosis and management of human disease. It contains original articles and critical reviews on all aspects of clinical cytology in its broadest sense, including: gynaecological and non-gynaecological cytology; fine needle aspiration and screening strategy. Cytopathology welcomes papers and articles on: ultrastructural, histochemical and immunocytochemical studies of the cell; quantitative cytology and DNA hybridization as applied to cytological material.
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