Circular RNA vaccines with long-term lymph node-targeting delivery stability after lyophilization induce potent and persistent immune responses

IF 4.7 1区生物学 Q1 MICROBIOLOGY

mBio Pub Date : 2023-12-11 DOI:10.1128/mbio.01775-23

Jiawu WanZongmei WangLingli WangLiqin WuChengguang ZhangMing ZhouZhen F. FuLing Zhao1National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China2Hubei Hongshan Laboratory, Wuhan, China3Key Laboratory of Preventive Veterinary Medicine of Hubei Province, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China, Xiang-Jin Meng

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Abstract

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冻干后具有长期淋巴结靶向输送稳定性的环状 RNA 疫苗可诱导强效持久的免疫反应

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来源期刊

mBio MICROBIOLOGY-

CiteScore

10.50

自引率

3.10%

发文量

762

审稿时长

1 months

期刊介绍： mBio® is ASM''s first broad-scope, online-only, open access journal. mBio offers streamlined review and publication of the best research in microbiology and allied fields.