Translation of an existing implantable cardiac monitoring device for measurement of gastric electrical slow-wave activity

Jarrah M. Dowrick, Lisa Jungbauer Nikolas, Sarah J. Offutt, Peter Tremain, Jonathan C. Erickson, Timothy R. Angeli-Gordon
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Abstract

Despite evidence that slow-wave dysrhythmia in the stomach is associated with clinical conditions such as gastroparesis and functional dyspepsia, there is still no widely available device for long-term monitoring of gastric electrical signals. Actionable biomarkers of gastrointestinal health are critically needed, and an implantable slow-wave monitoring device could aid in the establishment of causal relationships between symptoms and gastric electrophysiology. Recent developments in the area of wireless implantable gastric monitors demonstrate potential, but additional work and validation are required before this potential can be realized.

Abstract Image

改造现有的植入式心脏监测设备,测量胃电慢波活动
尽管有证据表明胃部慢波节律失常与胃痉挛和功能性消化不良等临床症状有关,但目前仍没有可长期监测胃电信号的广泛装置。胃肠道健康急需可操作的生物标志物,而植入式慢波监测设备可帮助确定症状与胃电生理学之间的因果关系。无线植入式胃监护仪领域的最新发展显示了其潜力,但在实现这一潜力之前还需要更多的工作和验证。
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