Céline Schulz, Quentin Lemaire, Alexandre Berthier, Amandine Descat, Mostafa Kouach, Anne-Sophie Vercoutter-Edouart, Ikram El Yazidi-Belkoura, Stéphan Hardivillé, Jean-François Goossens, Philippe Lefebvre, Tony Lefebvre
{"title":"Front Cover: Control of lipid metabolism by the dynamic and nutrient-dependent post-translational modification O-GlcNAcylation","authors":"Céline Schulz, Quentin Lemaire, Alexandre Berthier, Amandine Descat, Mostafa Kouach, Anne-Sophie Vercoutter-Edouart, Ikram El Yazidi-Belkoura, Stéphan Hardivillé, Jean-François Goossens, Philippe Lefebvre, Tony Lefebvre","doi":"10.1002/ntls.202320001","DOIUrl":null,"url":null,"abstract":"Post-translational modifications act as rheostats of protein activity. Many of them reflect environmental variations and allow the cell to give an adapted response to these changes. In this cover article #Ref, Céline Schulz and collaborators provide an in-depth overview of the still underrated role of the nutrient-dependent post-translational modification O-GlcNAcylation in the regulation of the metabolism of lipids, a very heterogenous family with very diverse functions.","PeriodicalId":501225,"journal":{"name":"Natural Sciences","volume":"31 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/ntls.202320001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Post-translational modifications act as rheostats of protein activity. Many of them reflect environmental variations and allow the cell to give an adapted response to these changes. In this cover article #Ref, Céline Schulz and collaborators provide an in-depth overview of the still underrated role of the nutrient-dependent post-translational modification O-GlcNAcylation in the regulation of the metabolism of lipids, a very heterogenous family with very diverse functions.