Briastecholide N: a New Chlorine-Containing Briarane Diterpenoid Deriving from Cultured

IF 0.8 4区化学 Q4 CHEMISTRY, ORGANIC

Heterocycles Pub Date : 2023-10-30 DOI:10.3987/com-23-14911

You-Ying Chen, Yueh-Wen Liu, Su-Ying Chien, Yu-Cheng Chen, Fu-Ching Chiu, Po-Wei Huang, I-Li Su, Zhi-Hong Wen, Hung-Tsung Lee, and Ping-Jyun Sung

引用次数: 0

Abstract

A new chlorine-containing briarane-type diterpenoid, briastecholide N (1) was isolated from cultured octocoral Briareum stechei via chemical screening. The structure of 1 was corroborated by 2D NMR experiments and confirmed backed by single-crystal X-ray diffraction analysis. The study found that 1 is capable of increasing the release of alkaline phosphatse (ALP) at 10 μM.

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Briastecholide N:一种新的含氯Briarane二萜

通过化学筛选，从培养的八月牙Briareum stechei中分离到一种新的含氯briarane型二萜类化合物briastecholide N(1)。通过二维核磁共振实验和单晶x射线衍射分析证实了1的结构。研究发现，1能增加10 μM下碱性磷酸酶(ALP)的释放。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Heterocycles 化学-有机化学

CiteScore

1.50

自引率

0.00%

发文量

108

审稿时长

1 months

期刊介绍： Since its inception in 1973 HETEROCYCLES has provided a platform for the rapid exchange of research in the areas of organic, pharmaceutical, analytical, and medicinal chemistry of heterocyclic compounds in addition to communications, papers, reviews, a special section of the journal presents newly-discovered natural products whose structure has recently been established. Another section is devoted to the total synthesis of previously documented natural products with heterocyclic ring systems. Due to the fact that the journal is able to publish articles within two months of receipt of the manuscripts, researchers in this field can obtain up-to-date information on heterocyclic research by reading Heterocycles regularly. Audience: Organic and Physical Organic Chemists, Biochemists, Pharmacologists and Scientists studying heterocyclic compounds

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