{"title":"Carvacrol is potential molecule for diabetes treatment.","authors":"Mustafa Hoca, Eda Becer, Hafize Seda Vatansever","doi":"10.1080/13813455.2023.2288537","DOIUrl":null,"url":null,"abstract":"<p><p>Diabetes is an important chronic disease that can lead to various negative consequences and complications. In recent years, several new alternative treatments have been developed to improve diabetes. Carvacrol found in essential oils of numerous plant species and has crucial potential effects on diabetes. The anti-diabetic effects of carvacrol have also been comprehensively studied in diabetic animal and cell models. In addition, carvacrol could improve diabetes through affecting diabetes-related enzymes, insulin resistance, insulin sensitivity, glucose uptake, anti-oxidant, and anti-inflammatory mechanisms. The use of carvacrol alone or in combination with anti-diabetic therapies could show a significant potential effect in the treatment of diabetes. This review contributes an overview of the effect of carvacrol in diabetes and anti-diabetic mechanisms.</p>","PeriodicalId":8331,"journal":{"name":"Archives of Physiology and Biochemistry","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Physiology and Biochemistry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/13813455.2023.2288537","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0
Abstract
Diabetes is an important chronic disease that can lead to various negative consequences and complications. In recent years, several new alternative treatments have been developed to improve diabetes. Carvacrol found in essential oils of numerous plant species and has crucial potential effects on diabetes. The anti-diabetic effects of carvacrol have also been comprehensively studied in diabetic animal and cell models. In addition, carvacrol could improve diabetes through affecting diabetes-related enzymes, insulin resistance, insulin sensitivity, glucose uptake, anti-oxidant, and anti-inflammatory mechanisms. The use of carvacrol alone or in combination with anti-diabetic therapies could show a significant potential effect in the treatment of diabetes. This review contributes an overview of the effect of carvacrol in diabetes and anti-diabetic mechanisms.
期刊介绍：
Archives of Physiology and Biochemistry: The Journal of Metabolic Diseases is an international peer-reviewed journal which has been relaunched to meet the increasing demand for integrated publication on molecular, biochemical and cellular aspects of metabolic diseases, as well as clinical and therapeutic strategies for their treatment. It publishes full-length original articles, rapid papers, reviews and mini-reviews on selected topics. It is the overall goal of the journal to disseminate novel approaches to an improved understanding of major metabolic disorders.
The scope encompasses all topics related to the molecular and cellular pathophysiology of metabolic diseases like obesity, type 2 diabetes and the metabolic syndrome, and their associated complications.
Clinical studies are considered as an integral part of the Journal and should be related to one of the following topics:
-Dysregulation of hormone receptors and signal transduction
-Contribution of gene variants and gene regulatory processes
-Impairment of intermediary metabolism at the cellular level
-Secretion and metabolism of peptides and other factors that mediate cellular crosstalk
-Therapeutic strategies for managing metabolic diseases
Special issues dedicated to topics in the field will be published regularly.
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