Hypernatremic chloride-depletion metabolic alkalosis successfully treated with high cation-gap amino acids: a case report.

IF 1 Q4 UROLOGY & NEPHROLOGY

CEN Case Reports Pub Date : 2024-08-01 Epub Date: 2023-11-22 DOI:10.1007/s13730-023-00837-z

Akihiro Ryuge, Shogo Nagamine, Masashi Saito, Naoki Matsumoto, Marina Asano

引用次数: 0

Abstract

Normal saline (NS) is recommended for the treatment of chloride-depletion alkalosis (CDA). However, its use in patients with drinking water restrictions or fluid volume deficiencies may lead to hypernatremia. We report the case of a 42-year-old Japanese man with ileus due to sigmoidal volvulus, who presented with CDA. After endoscopic decompression, NS was administered to treat the CDA. Despite the administration of NS, CDA persisted and hypernatremia developed. The infusion was then changed to high cation-gap amino acids (HCG-AA), which improved both metabolic alkalosis and hypernatremia. Thus, HCG-AA may be useful for the treatment of hypernatremia in patients with CDA.

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高阳离子间隙氨基酸成功治疗高钠血症氯消耗代谢性碱中毒1例。

生理盐水(NS)被推荐用于治疗氯化物缺乏性碱中毒(CDA)。然而，在饮水限制或液体量不足的患者中使用它可能导致高钠血症。我们报告一个42岁的日本男子肠梗阻由于乙状结肠扭转，谁提出了CDA。内镜下减压后，给予NS治疗CDA。尽管给予NS治疗，CDA仍持续存在并出现高钠血症。然后将输注改为高阳离子间隙氨基酸(HCG-AA)，可改善代谢性碱中毒和高钠血症。因此，HCG-AA可能有助于治疗CDA患者的高钠血症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

CEN Case Reports UROLOGY & NEPHROLOGY-

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： Clinical and Experimental Nephrology (CEN) Case Reports is a peer-reviewed online-only journal, officially published biannually by the Japanese Society of Nephrology (JSN). The journal publishes original case reports in nephrology and related areas. The purpose of CEN Case Reports is to provide clinicians and researchers with a forum in which to disseminate their personal experience to a wide readership and to review interesting cases encountered by colleagues all over the world, from whom contributions are welcomed.