Combined hormonal contraception

Anna Glasier
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引用次数: 0

Abstract

Combined oral contraception is now available as oral, transdermal, vaginal and injectable preparations. Only the pill and patch are currently marketed in the UK. Most of the data come from the oral preparation (the combined pill), which has been marketed for more than 40 years and used by millions of women. Used perfectly, combined hormonal contraception is highly effective (failure rate 1/1000), because it works by inhibiting ovulation. In typical use, however, mistakes are made, and pill failure rates are about 8%. Serious cardiovascular side-effects (heart attack, stroke and venous thromboembolism) are rare. The risk of venous thromboembolism varies with the type of progestogen. Breast and cervical cancer are both increased in users, though the absolute risk is small. Prescribing should not be over-medicalized.

激素联合避孕
联合口服避孕药现在有口服、透皮、阴道和注射制剂。目前只有药丸和贴片在英国销售。大多数数据来自口服制剂(复方药片),该制剂已上市40多年,被数百万妇女使用。使用得当,联合激素避孕是非常有效的(失败率为1/1000),因为它是通过抑制排卵来起作用的。然而,在典型的使用中,会出现错误,药丸的失败率约为8%。严重的心血管副作用(心脏病发作、中风和静脉血栓栓塞)是罕见的。静脉血栓栓塞的风险因孕激素的类型而异。尽管绝对风险很小,但服用者患乳腺癌和宫颈癌的风险都有所增加。处方不应过度医疗化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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