Patterns and Life Course Determinants of Black-White Disparities in Biological Age Acceleration: A Decomposition Analysis.

IF 3.6 1区社会学 Q1 DEMOGRAPHY

Demography Pub Date : 2023-12-01 DOI:10.1215/00703370-11057546

Courtney E Boen, Y Claire Yang, Allison E Aiello, Alexis C Dennis, Kathleen Mullan Harris, Dayoon Kwon, Daniel W Belsky

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引用次数: 0

Abstract

Despite the prominence of the weathering hypothesis as a mechanism underlying racialized inequities in morbidity and mortality, the life course social and economic determinants of Black-White disparities in biological aging remain inadequately understood. This study uses data from the Health and Retirement Study (n = 6,782), multivariable regression, and Kitagawa-Blinder-Oaxaca decomposition to assess Black-White disparities across three measures of biological aging: PhenoAge, Klemera-Doubal biological age, and homeostatic dysregulation. It also examines the contributions of racial differences in life course socioeconomic and stress exposures and vulnerability to those exposures to Black-White disparities in biological aging. Across the outcomes, Black individuals exhibited accelerated biological aging relative to White individuals. Decomposition analyses showed that racial differences in life course socioeconomic exposures accounted for roughly 27% to 55% of the racial disparities across the biological aging measures, and racial disparities in psychosocial stress exposure explained 7% to 11%. We found less evidence that heterogeneity in the associations between social exposures and biological aging by race contributed substantially to Black-White disparities in biological aging. Our findings offer new evidence of the role of life course social exposures in generating disparities in biological aging, with implications for understanding age patterns of morbidity and mortality risks.

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黑人-白人生物年龄加速差异的模式和生命历程决定因素:一个分解分析。

尽管风化假说作为发病率和死亡率的种族化不平等的一种机制，但黑人和白人生物衰老差异的生命过程的社会和经济决定因素仍然没有得到充分的理解。本研究使用来自健康与退休研究(n = 6,782)的数据、多变量回归和Kitagawa-Blinder-Oaxaca分解来评估黑人和白人在三种生物衰老指标上的差异:表型年龄、klemera - double生物年龄和稳态失调。它还检查了种族差异在生命历程中的贡献，社会经济和压力暴露以及对这些暴露的脆弱性在生物衰老方面的黑人-白人差异。在所有结果中，黑人个体相对于白人个体表现出加速的生物衰老。分解分析表明，在生物衰老测量中，生命过程中社会经济暴露的种族差异约占种族差异的27%至55%，社会心理压力暴露的种族差异占7%至11%。我们发现很少有证据表明社会暴露和种族间生物衰老之间的异质性在很大程度上导致了黑人和白人在生物衰老方面的差异。我们的研究结果为生命过程中社会暴露在产生生物衰老差异中的作用提供了新的证据，这对理解发病率和死亡率风险的年龄模式具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Demography DEMOGRAPHY-

CiteScore

5.90

自引率

2.90%

发文量

期刊介绍： Since its founding in 1964, the journal Demography has mirrored the vitality, diversity, high intellectual standard and wide impact of the field on which it reports. Demography presents the highest quality original research of scholars in a broad range of disciplines, including anthropology, biology, economics, geography, history, psychology, public health, sociology, and statistics. The journal encompasses a wide variety of methodological approaches to population research. Its geographic focus is global, with articles addressing demographic matters from around the planet. Its temporal scope is broad, as represented by research that explores demographic phenomena spanning the ages from the past to the present, and reaching toward the future. Authors whose work is published in Demography benefit from the wide audience of population scientists their research will reach. Also in 2011 Demography remains the most cited journal among population studies and demographic periodicals. Published bimonthly, Demography is the flagship journal of the Population Association of America, reaching the membership of one of the largest professional demographic associations in the world.