[Comparison of in vitro activity of ciprofloxacin and pefloxacin against strains isolated from clinical material].

M Kumelj, A Rus, E Music
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引用次数: 0

Abstract

The susceptibility of 392 strains of pathogenic bacteria isolated from clinical material of hospitalized patients in Institute for Chest Diseases Golnik were studied. 100 strains of Escherichia coli, 56 strains of Enterobacter spp., 40 strains of Proteus mirabilis, 50 strains of Gram negative nonfermentative bacteria, 46 strains of Pseudomonas aeruginosa and 100 strains of Staphylococcus aureus were tested. Minimal inhibitory concentrations of ciprofloxacin and pefloxacin were determined by agar dilution test. The susceptibility of tested strains is greater to ciprofloxacin, except susceptibility of strains of Staphylococcus aureus, which is greater to pefloxacin. Strains of nonfermentative bacteria have lower susceptibility to both quinolones.

[环丙沙星与培氟沙星对临床分离菌株体外活性的比较]。
对戈尔尼克胸科医院住院患者临床材料中分离的392株病原菌进行了药敏试验。检测大肠埃希菌100株、肠杆菌56株、奇异变形杆菌40株、革兰氏阴性非发酵菌50株、铜绿假单胞菌46株、金黄色葡萄球菌100株。用琼脂稀释法测定环丙沙星和培氟沙星的最低抑菌浓度。除金黄色葡萄球菌对培氟沙星的敏感性较大外,其余菌株对环丙沙星的敏感性较大。非发酵菌株对这两种喹诺酮类药物的敏感性较低。
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