Testicular involvement in mantle cell lymphoma: An analysis of 16 patients.

IF 0.7 Q4 HEMATOLOGY
Samer Alkhalili , Dharmini Manogna , Hana Safah , Elizabeth Ellent , Walter Beversdorf , Ruby Arora , Nakhle S. Saba
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引用次数: 0

Abstract

Mantle cell lymphoma (MCL) with testicular involvement is a rare presentation and only a few cases have been described in the literature. We present a case of MCL with testicular involvement and the first analysis of all previously reported cases assessing trends in immunohistochemical features, prognostic indicators, and survival. Our data suggest that among all MCL, testicular MCL is more likely to present with aggressive features: blastoid/pleomorphic morphology, high Ki-67 proliferative index, and CNS involvement. Testicular MCL is also associated with shorter overall survival.

套细胞淋巴瘤累及睾丸16例分析。
套细胞淋巴瘤(MCL)累及睾丸是一种罕见的表现,只有少数病例在文献中被描述。我们报告了一例累及睾丸的MCL病例,并首次分析了所有先前报道的病例,评估其免疫组织化学特征、预后指标和生存率的趋势。我们的数据表明,在所有MCL中,睾丸MCL更有可能呈现侵袭性特征:囊胚/多形性形态、高Ki-67增殖指数和中枢神经系统受累。睾丸MCL也与较短的总生存期相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Leukemia Research Reports
Leukemia Research Reports Medicine-Oncology
CiteScore
1.70
自引率
0.00%
发文量
70
审稿时长
23 weeks
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