Antifungal Activity of Solanum Anguivi Lam (Solanaceae) on Candida Albicans

Ouattara Sitapha, Kporou Kouassi Elisée, Kra Adou Koffi Mathieu, Appia Franck Hermann Desire, YAPO Adou Francis, Djaman Allico Joseph
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Abstract

In Ivory Coast, as elsewhere in Africa, Solanum anguivi Lam (or Solanum distichum) is generally used in traditional medicine to treat bacterial and fungal infections. Given the importance of this plant, the 70%, 80% and 100% extracts of fresh and dried fruits were evaluated on the in vitro growth of Candida albicans. Antifungal tests were carried out by plating 1000 cells of each isolate on Sabouraud agar medium, using the double dilution method in inclined tubes. Both extracts were active on the different strains tested, according to a dose-response relationship based on the principle of the method used. Extracts from fresh fruit showed good activity on C. albicans.
龙葵对白色念珠菌的抑菌活性研究
在科特迪瓦,和非洲其他地方一样,龙葵(或龙葵)通常在传统医学中用于治疗细菌和真菌感染。考虑到该植物的重要性,研究了70%、80%和100%鲜果提取物和干果提取物对白色念珠菌体外生长的影响。采用斜管双倍稀释法,将每个分离株的1000个细胞在Sabouraud琼脂培养基上进行抑菌试验。根据基于所用方法原理的剂量-反应关系,这两种提取物对不同的菌株都有活性。新鲜水果提取物对白色念珠菌有较好的抑制作用。
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