Concentration of Interferon - gamma in Respiratory Disease Infected Chickens Caused by Mycoplasma gallisepticum

Noor Hussein Abdul-Rahman, Ghassan Hamdan Jameel, Talib Jawad Kadhim
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Abstract

Mycoplasma gallisepticum is commonly involved in the polymicrobial "chronic respiratory disease" in broiler chickens, leading to increased condemnations in the processing plant. In layers and breeders, it is usually subclinical, but causes a reduction in the number of eggs laid per hen over the production cycle. The present study aim to sero-identification of the Mycoplasma gallisepticum and study the concentration of interferon gamma. Sixty seven broiler chickens with respiratory signs (infected group), and fifteen healthy chickens considered as control group were used in this study. Blood samples were collected from all groups to perform in enzyme-linked immunosorbent test to identification antibodies for Mycoplasma gallisepticum and the level of interferon gamma. The result was shown (32/67) sample from infected chicken was positive for Mycoplasma gallisepticum and the level of INF-Gamma is significantly higher in the positive chicken for Mycoplasma gallisepticum infection at (102.34 ± 31.37) pg/ml when compared to control group at found (74.68 ± 12.75) pg/ml. The conclusion that increasing the level of INF-Gamma was affected in the increasing the susceptible to Mycoplasma gallisepticum infection and caused chronic respiratory disease infected to chickens in Iraq
鸡败菌支原体感染呼吸道疾病鸡体内干扰素- γ浓度的变化
鸡败菌支原体通常与肉鸡的多微生物“慢性呼吸道疾病”有关,导致加工厂受到越来越多的谴责。在蛋鸡和种鸡中,它通常是亚临床的,但会导致每只母鸡在生产周期内产蛋量的减少。本研究旨在对鸡败支原体进行血清鉴定,并对血清干扰素γ浓度进行研究。以67只有呼吸体征的肉鸡为感染组,15只健康肉鸡为对照组。采集各组血标本,进行酶联免疫吸附试验,鉴定鸡败支原体抗体和干扰素γ水平。结果显示:(32/67)感染鸡鸡支原体阳性,阳性鸡鸡中nf - gamma的水平为(102.34±31.37)pg/ml,显著高于对照组(74.68±12.75)pg/ml。结论在伊拉克鸡中,inf - γ水平的升高与鸡对鸡败菌支原体感染的易感性增加有关,并引起鸡感染慢性呼吸道疾病
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