Effects of 0.15% ropivacaine alone and combination with sufentanil on epidural labor analgesia and adverse reactions

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

African Health Sciences Pub Date : 2023-10-11 DOI:10.4314/ahs.v23i3.66

Huanhui Zhong, Yongdong Wang, Yiqun Wang, Heng Li

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引用次数: 0

Abstract

Objective: The aim of this study was to compare the impacts of 0.15% ropivacaine alone and 0.15% ropivacaine combined withsufentanil on epidural labor analgesia. Methods: A total of 297 eligible primiparae were randomly divided into group A (n=149, 0.15% ropivacaine + sufentanil) andgroup B (n=148, 0.15% ropivacaine). Visual analogue scale (VAS) scores prior to analgesia and 20 min following epidural medication,the maximum VAS score during labor, dosage of analgesic drugs, modified Bromage score, satisfaction degree, laborduration, delivery mode, 1-min and 5-min Apgar scores of newborns, adverse reactions during analgesia, and fever during laborwere recorded. Results: Group A and B had similar VAS scores 20 min following epidural medication and maximum score during labor(P>0.05), which significantly fell compared with those before labor analgesia (P<0.05). The occurrence rates of nausea andvomiting were of significant difference (P<0.05). Conclusion: 0.15% ropivacaine alone achieves a comparable epidural labor analgesia effect to that of 0.15% ropivacaine + 0.05μg/mL sufentanil on primiparae. Keywords: Ropivacaine; sufentanil; epidural labor analgesia; adverse reaction.

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0.15%罗哌卡因单用及联合舒芬太尼对硬膜外分娩镇痛及不良反应的影响

目的:比较0.15%罗哌卡因单用与0.15%罗哌卡因联合舒芬太尼对硬膜外分娩镇痛的影响。方法:将297例符合条件的初产妇随机分为A组(149例，0.15%罗哌卡因+舒芬太尼)和B组(148例，0.15%罗哌卡因)。记录镇痛前和硬膜外用药后20 min视觉模拟评分(VAS)、分娩时最高VAS评分、镇痛药物用量、改良Bromage评分、满意度、产程、分娩方式、新生儿1 min和5 min Apgar评分、镇痛时不良反应、产中发热情况。结果:A、B组患者在硬膜外用药后20 min VAS评分与分娩时最高评分相近(P>0.05)，与分娩镇痛前比较差异有统计学意义(P>0.05)。恶心、呕吐发生率差异有统计学意义(p < 0.05)。结论:0.15%罗哌卡因单用与0.15%罗哌卡因+ 0.05μg/mL舒芬太尼单用对初产妇硬膜外镇痛效果相当;关键词:Ropivacaine;舒芬太尼;硬膜外分娩镇痛;不良反应。

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来源期刊

African Health Sciences MEDICINE, GENERAL & INTERNAL-

CiteScore

2.30

自引率

0.00%

发文量

179

审稿时长

>12 weeks

期刊介绍： The African Health Sciences is an internationally refereed journal publishing original articles on research, clinical practice, public health, policy, planning, implementation and evaluation, in the health and related sciences relevant to Africa and the tropics. Its objectives are to: Advocate for and promote the growth of reading culture in sub Saharan Africa; Provide a high quality journal in which health and policy and other researchers and practitioners in the region can and world wide, can publish their work; Promote relevant health system research and publication in the region including alternative means of health care financing, the burden of and solution of health problems in marginalized urban and rural communities amongst the displaced and others affected by conflict; Promote research and the systematic collection and collation and publication of data on diseases and conditions of equity and influence; Promote development of evidence-based policies and guidelines for clinical, public health and other practitioners. African Health Sciences acknowledges support provided by the African Health Journals Partnership Project that is funded by the US National Institutes of Health (through the National Library of Medicine and the Fogarty International Center) and facilitated by the Council of Science Editors.