Gallic Acid: A Wonderful Remedy in Medicinal Field

IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE

Current Traditional Medicine Pub Date : 2023-10-11 DOI:10.2174/0122150838266828231005055236

Anmol saini, Vishakha D. Saini, Renu Saharan, Suresh Kumar

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引用次数: 0

Abstract

Abstract: GA (Gallic acid) belongs to the phenolic molecule that is naturally present in plants, and has an assortment of medicinal benefits on inflammation, obesity, cancer, the heart, neurological system, and the proliferation of cells. In more recent research, the anti-cancer effects via biological mechanisms such as angiogenesis, migration, metastasis, cell cycle arrest, and apoptosis have been demonstrated. Anti-cancer activities of gallic acid are affected through the biological methods which involve reluctance of tumor migration, inflammation, etc. Numerous degenerative diseases, namely blood-vascular, ageing, inflammatory contagion and malignancy are brought on owing to the free radical damage because of the excess amount of free radicals produced and accretion. We carried out a comprehensive examination of the literature employing the expression of gallic acid. To review the most current advancements and clinical investigations for the pharmacological effects of gallic acid, recognized research from various reputable organizations and sites including Scopus, ClinicalTrails.gov, Science Direct, and PubMed were analyzed. This review, which offers a succinct description of gallic acid, updates the contents of clinical research and patent data, it brings forth the elaborate attainment regarding the various abundant therapeutic efficacies along with the extraction methodology of the drug that is used to obtain it, including microwave-assisted extraction and maceration extraction, among others, as well as non-chromatographic and chromatographic techniques for its isolation and quantification. Antifungal, antiulcer, antiviral, anticancer, and antibacterial properties are just a few of the pharmacological effects of naturally occurring gallic acid.

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没食子酸:一种神奇的药物

摘要:GA(没食子酸)是一种天然存在于植物中的酚类分子，对炎症、肥胖、癌症、心脏、神经系统和细胞增殖具有多种药用价值。在最近的研究中，通过血管生成、迁移、转移、细胞周期阻滞和细胞凋亡等生物机制证明了抗癌作用。没食子酸的抗癌作用是通过抑制肿瘤迁移、抑制炎症等生物学途径发挥的。许多退行性疾病，即血管、衰老、炎症性传染和恶性肿瘤，都是由于自由基的过量产生和积聚而引起的。我们对采用没食子酸表达的文献进行了全面的检查。为了回顾没食子酸药理作用的最新进展和临床研究，我们分析了来自各种知名组织和网站的公认研究，包括Scopus、ClinicalTrails.gov、Science Direct和PubMed。本文对没食子酸进行了简要的描述，更新了没食子酸的临床研究内容和专利资料，详细介绍了没食子酸的各种丰富的治疗功效，以及用于获得没食子酸的药物的提取方法，包括微波辅助提取和浸渍提取等，以及用于分离和定量的非色谱和色谱技术。抗真菌、抗溃疡、抗病毒、抗癌和抗菌只是天然没食子酸药理作用的一小部分。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Traditional Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： Current Traditional Medicine covers all the aspects of the modernization and standardization research on traditional medicine of the world, e.g. chemistry, pharmacology, molecular mechanism, systems biology, proteomics, genomics, metabolomics, safety, quality control, clinical studies of traditional Chinese, Ayurvedic, Unani, Arabic and other ethnomedicine. Each issue contains updated comprehensive in-depth/mini reviews along with high quality original experimental research articles. Current Traditional Medicine is a leading and important international peer-reviewed journal reflecting the current outstanding scientific research progresses of the global traditional, indigenous, folk and ethnologic medicine. It provides a bridge connected the tradition medicine system to the modern life science with the efforts of top scientists, as well as a resource to pursuit the solutions for the existing common issues in the traditional medicine.