Irisin; a myokine with therapeutic and diagnostic potential in clinical dentistry

Alina Saleem, None Sarah Ghafoor
{"title":"Irisin; a myokine with therapeutic and diagnostic potential in clinical dentistry","authors":"Alina Saleem, None Sarah Ghafoor","doi":"10.47391/jpma.8360","DOIUrl":null,"url":null,"abstract":"Irisin is a novel adipomyokine which has extensive systemic and local effects in different tissues of the body. The scientific interest in understanding the physiological roles of irisin in the body has increased tremendously in the past few years due to its vast therapeutic potential in different fields of medicine. The current narrative review was planned to describe the molecular mechanisms by which irisin regulates oral hard and soft tissues. The information gleaned provided useful insights for future researchers to investigate newly discovered roles of irisin in craniofacial health and disease, and to explore the potential of irisin as a promising therapeutic and diagnostic agent in clinical dentistry. Key Words: FNDC5, Irisin, Human periodontal ligament cell, Human dental pulp stem cell, Bone, Regeneration.","PeriodicalId":16673,"journal":{"name":"Journal of Pakistan Medical Association","volume":"65 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pakistan Medical Association","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47391/jpma.8360","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Irisin is a novel adipomyokine which has extensive systemic and local effects in different tissues of the body. The scientific interest in understanding the physiological roles of irisin in the body has increased tremendously in the past few years due to its vast therapeutic potential in different fields of medicine. The current narrative review was planned to describe the molecular mechanisms by which irisin regulates oral hard and soft tissues. The information gleaned provided useful insights for future researchers to investigate newly discovered roles of irisin in craniofacial health and disease, and to explore the potential of irisin as a promising therapeutic and diagnostic agent in clinical dentistry. Key Words: FNDC5, Irisin, Human periodontal ligament cell, Human dental pulp stem cell, Bone, Regeneration.
Irisin;一种在临床牙科中具有治疗和诊断潜力的肌因子
鸢尾素是一种新型脂肪代谢因子,在人体不同组织中具有广泛的全身和局部作用。由于鸢尾素在不同的医学领域具有巨大的治疗潜力,在过去几年中,人们对鸢尾素在人体中的生理作用的科学兴趣急剧增加。本文拟从鸢尾素调节口腔软组织和硬组织的分子机制进行综述。这些信息为今后研究鸢尾素在颅面健康和疾病中的新作用提供了有益的见解,并为探索鸢尾素作为临床牙科治疗和诊断药物的潜力提供了有益的见解。关键词:FNDC5,鸢尾素,人牙周韧带细胞,人牙髓干细胞,骨,再生
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信