Paraneoplastic Cushing syndrome caused by a pancreatic neuroendocrine tumor: a case report

Abstract

Background: Endogenous Cushing syndrome results from uncontrolled overproduction of cortisol. Paraneoplastic Cushing syndrome (PCS) is an uncommon etiology of endogenous hypercortisolism caused generally by bronchial and thymic adrenocorticotropic hormone (ACTH)-producing tumors. Pancreatic neuroendocrine tumors (NETs) have been reported in only few cases.