E2F1-mediated Up-regulation of NCAPG Promotes Hepatocellular carcinoma Development by Inhibiting Pyroptosis

IF 3.1 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Journal of Clinical and Translational Hepatology Pub Date : 2023-10-30 DOI:10.14218/jcth.2022.00292

Cuicui Xiao, Jiao Gong, Yusheng Jie, Weicheng Liang, Yan Tai, Wei Qin, Tongyu Lu, Yutian Chong, Ziqing Hei, Bo Hu, Qi Zhang

引用次数: 0

Abstract

Background and AimsAs a subunit of the condensin complex, NCAPG has an important role in maintaining chromosome condensation, but its biological function and regulatory mechanism in hepatocellular carcinoma (HCC) remains undefined.

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e2f1介导的NCAPG上调通过抑制肝细胞凋亡促进肝细胞癌的发展

背景与目的NCAPG是凝缩蛋白复合体的一个亚基，在维持染色体凝缩中起重要作用，但其在肝细胞癌(HCC)中的生物学功能和调控机制尚不明确。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical and Translational Hepatology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

6.40

自引率

2.80%

发文量

496