Effect of the long-term storage methods on the stability of cartilage biomechanical parameters

Blanka Žaloudková, Šárka Sekorová, Barbora Kopecká, Daniel Kytýř
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引用次数: 0

Abstract

Long-term stability of the tissue product in terms of mechanical parameters is a key factor for its expiration date. For the investigation of storage effects on the cartilage tissues the experimental mechanical loading test combined with XCT scanning for the irregular shape inspection was performed. The samples were preserved according to three different protocols using the deep-freezing and two types of saline solution preservation. The stability of the biomechanical parameters was tested within annual intervals. All samples were subjected to uni-axial compression loading using the in-house developed compact table top loading device in displacement-driven mode. Based on the measurements, the results are represented in the form of stress-strain curves and quantified as elastic modulus and ultimate compression stress. It can be concluded that no significant difference was found in neither the mechanical properties of the samples nor in the effects of each preservational method.
长期保存方法对软骨生物力学参数稳定性的影响
纸巾产品在力学参数方面的长期稳定性是决定其有效期的关键因素。为了研究软骨组织的储存效应,我们进行了实验力学加载试验,并结合XCT扫描进行不规则形状检查。根据三种不同的保存方案,分别使用深度冷冻和两种盐水溶液保存。每隔一年检测生物力学参数的稳定性。所有样品均采用自行研制的紧凑台式加载装置进行单轴压缩加载,加载方式为位移驱动。根据测量结果,将结果以应力-应变曲线的形式表示,并量化为弹性模量和极限压应力。可以得出结论,无论是样品的力学性能还是每种保存方法的效果都没有显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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