MICROBIOLOGICAL CHARACTERISTICS OF THE LAPAROTOMIC WOUND, WHEN COMPLETE EVENTRATION BEGINNING, IN THE ONCOLOGICAL PROCESS

Abstract

The aim of the study –to study the peculiarities of the qualitative and quantitative compositionof the microflora of the wound exudate of the laparotomy wound, complicated by the eventration,depending on its degree, in patients with malignant neoplasms of the abdominal cavity.Materials and methods.28 patients with malignant neoplasms of abdominal organs who hadpostoperative eventration were studied. The main group consisted of 12 patients who hada complete eventration (grade II-IV). The comparison group was formed by 16 patients whohad subcutaneous eventration (I degree). The collection of biological material was carriedout during the 8th day of the early postoperative period, by bacteriological examinationof the wound exudate, during dressings. Species composition of microorganisms, theirpopulation level, the coefficient of constancy, the frequency of species detection, thecoefficient of significance, the coefficient of quantitative dominance was studied.Results. When eventration II-IV degrees occurs, against a background of the oncologicalprocess, a probable predominance of the number of strains of E. coli, S. aureus and m/o ofthe genus Proteus is noted, and the number of strains of E. coli is likely to prevail during allperiods of observation. During the development of II-IV degrees of eventration, due to theoncological process, in the exudate of the laparotomy wound, there is a probable predominanceof the population level of E. coli, S. aureus and m/o of the genus Proteus. The dominantmicroorganism, according to the determined coefficient of quantitative dominance, at alldegrees of eventration, throughout the entire period of the study, is E. coli, and Enterococcusfaecalis is in the second place. At the same time, at all degrees of eventration, high numbers ofthe coefficient of quantitative dominance in S. aureus are noted on the 6-8th day of the study. Conclusions. With the development of postoperative eventration of II-IV degrees, inpatients with malignant neoplasms of the abdominal cavity, a probable increase in thenumber of strains sown and the population level of microorganisms in the laparotomywound exudate with E. coli, S. aureus and microorganisms of the genus Proteus is noted.In patients with malignant neoplasms of the abdominal cavity, with the occurrence ofII-IV degrees of postoperative eventuration, the dominant microorganisms of the woundexudate are E. coli and Enterococcus faecalis and microorganisms of the genus Proteus.