Formulation and Evaluation of Herbal Antifungal Cream of Zingiber officinale

Abstract

The aim of the study was to formulate a cream containing a composition to treat fungal infections of the skin and improve skin properties. This preparation belongs to medicinal creams containing antifungal agents. It reveals a formula for treating skin fungal infections. For skin infections, a topical approach is the best option. Developing a local drug delivery system with systemic action may be advantageous for a variety of drugs, as it offers many advantages over traditional drug administration routes. Ginger extract is an active pharmaceutical ingredient (API) used to treat fungal skin infections. The cream base also contains two primary and secondary emulsifiers, a waxy substance, a co-solvent, two preservatives, a buffer, a humectant, and water. When the active ingredients combine, they exert a powerful antifungal effect. Several experiments were performed to evaluate the physico-chemical properties of formulated creams, including: B. Visual inspection, pH measurement, homogeneity, removal test, skin irritation test, viscosity, spreadability test, saponification value, acid value, etc. The antifungal effect of the cream was further analyzed using nutrient agar. The medicated cream had good viscosity and color. However, the scent of ginger was characteristic.