Antioxidation and anti-inflammatory activities of blended essential oil

IF 0.2 Q4 HEALTH CARE SCIENCES & SERVICES

Healthcare in Lowresource Settings Pub Date : 2023-09-11 DOI:10.4081/hls.2023.11548

Suriya Chaiwong, Kunthasaya Akkarasiritharattana, Khamjira Jarmkom, Punyanut Amorndoljai

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Abstract

The mixtures of essential oils are increasing popularly in holistic medicine. The different ratios of oil components in the preparation can result in different health benefits. Therefore, this study aimed to develop a mixture of essential oil formulation having promising bioactivities for pharmaceutical and cosmetic applications. The five popular essential oils including vetiver oil, lavender oil, eucalyptus oil, lemongrass oil, and phlai oil were selected for blended formulation. The selected oils were mixed in a suitable ratio and their antioxidant and anti-inflammatory activities were evaluated using 2,2-Diphenyl-1-picrylhydrazyl radical scavenging and nitric oxide (NO) radical scavenging, respectively. The prepared blended essential oil formulation had clear yellow-pale color and good smell. The blended oil showed good antioxidative activity by acting as a hydrogen donator. However, the blended oil presents mild anti-inflammatory activity via NO quenching action. The results of this study exposed that the developed blended essential oil formulation has promising properties to be used as a natural antioxidant as well as an anti-inflammatory agent in cosmetic and pharmaceutical applications.

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混合精油的抗氧化和抗炎活性

精油的混合物在整体医学中越来越受欢迎。制剂中不同比例的油成分可产生不同的健康效益。因此，本研究旨在开发一种具有良好生物活性的混合精油制剂，用于制药和化妆品领域。选取香根草油、薰衣草油、桉树油、柠檬草油、佛莱油等5种流行精油进行混合配方。将所选油脂按适当比例混合，分别用清除2,2-二苯基-1-苦味酰肼基自由基和清除一氧化氮(NO)自由基的方法评价其抗氧化和抗炎活性。所制备的混合精油配方色泽黄淡，气味好。混合油作为供氢体表现出良好的抗氧化活性。然而，调和油通过NO猝灭作用表现出温和的抗炎活性。本研究结果表明，所开发的混合精油制剂在化妆品和制药应用中具有作为天然抗氧化剂和抗炎剂的良好性能。

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