COMPARISON OF MALONDIALDEHYDE LEVELS AMONG PATIENTS WITH SANDBLASTED ACID-ETCHED AND ANODIZED SURFACE DENTAL IMPLANTS: A PROSPECTIVE CLINICAL STUDY

Q3 Dentistry
Arvina Rajasekar, Sheeja S Varghese
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引用次数: 0

Abstract

Objective: Inflammation that occur as a part of body's response to implant-tissue contact can result in oxidative stress. Therefore, exploring the oxidative stress around different surface treated dental implants is essential to improve the performance of implants. The purpose of this study was to detect and measure the level of malondialdehyde (MDA), oxidative stress marker among SLA, SLActive and TiUnite implant surfaces. Materials and Methods: Subjects with healthy dental implant were categorized into Group 1: SLA (n=25), Group 2: SLActive (n=25), Group 3: TiUnite (n=25). Peri-implant crevicular fluid (PICF) was collected and MDA was quantified using ELISA kit. Statistical analysis was performed using one-way ANOVA, followed by Tukey’s HSD post hoc. Results: The MDA level was high in group 3 (6.49±0.29 nmol/mL) followed by group 1 (5.37±0.47 nmol/mL) and group 2 (4.37±0.22 nmol/mL). There was a significant difference in MDA levels between the three groups (p = 0.00). Also, pairwise comparison showed a statistically significant difference between the groups (p = 0.00). Conclusion: Malondialdehyde level in peri-implant crevicular fluid was high around TiUnite dental implant as compared to SLA and SLActive implants.
喷砂酸蚀和阳极表面牙种植体患者丙二醛水平的比较:一项前瞻性临床研究
目的:炎症是机体对植入物与组织接触反应的一部分,可导致氧化应激。因此,研究不同表面处理的种植体周围的氧化应激对提高种植体的性能至关重要。本研究的目的是检测和测量SLA、SLActive和TiUnite种植体表面氧化应激标志物丙二醛(MDA)的水平。材料与方法:健康种植体患者分为组1:SLA (n=25),组2:SLActive (n=25),组3:TiUnite (n=25)。采集种植体周围沟液(PICF), ELISA检测丙二醛(MDA)含量。采用单因素方差分析进行统计分析,随后采用Tukey’s HSD事后分析。结果:MDA水平以3组高(6.49±0.29 nmol/mL),其次为1组(5.37±0.47 nmol/mL), 2组(4.37±0.22 nmol/mL)。三组间MDA水平差异有统计学意义(p = 0.00)。两两比较,两组间差异有统计学意义(p = 0.00)。结论:与SLA和SLActive种植体相比,TiUnite种植体周围沟液中丙二醛含量较高。
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来源期刊
CiteScore
1.20
自引率
0.00%
发文量
46
期刊介绍: MEDICAL IMPLANTS are being used in every organ of the human body. Ideally, medical implants must have biomechanical properties comparable to those of autogenous tissues without any adverse effects. In each anatomic site, studies of the long-term effects of medical implants must be undertaken to determine accurately the safety and performance of the implants. Today, implant surgery has become an interdisciplinary undertaking involving a number of skilled and gifted specialists. For example, successful cochlear implants will involve audiologists, audiological physicians, speech and language therapists, otolaryngologists, nurses, neuro-otologists, teachers of the deaf, hearing therapists, cochlear implant manufacturers, and others involved with hearing-impaired and deaf individuals.
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