The Content of Minor Elements in the Breast Collection No. 4

Q3 Pharmacology, Toxicology and Pharmaceutics
I. V. Gravel, D. V. Levushkin
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Abstract

Introduction. Trace elements are an essential part of the human body, but about 80 % of the human population notes an imbalance in their content. Medicinal plants contain minerals in an accessible and digestible form together with biologically active substances. Medicinal herbal preparations are very popular for the prevention and as part of the complex therapy of various diseases. However, information about the content of trace elements in multicomponent medicinal herbal preparations is very limited. Therefore, it is necessary to study the mineral composition, which will allow us to consider plant collections as an additional source of trace elements. Aim. The purpose of our study was to study the content of trace elements (B, Si, Al, Ba, Sr, Ti) in breast collection No. 4, its components and aqueous extracts from them. Materials and methods. The objects of the study were breast collection No. 4, its individual components and aqueous extracts from them. Infusions from the samples were obtained according to the instructions for use on the packaging of a medicinal herbal preparation. The samples were prepared for analysis with a mixture of concentrated nitric acid and water deionized in the Milestone Ethos Up microwave system (Milestone, Italy). The analysis was carried out by atomic emission spectrometry with inductively coupled plasma on the ISP-NPP 720-ES device (Agilent Technologies, USA). Results and discussion. It was found that the concentrations of Si, Al, B, Sr, Ba, Ti in individual components of the collection varied in the range of 2.9–1240 mg/kg, the transition of trace elements to aqueous extracts was 0.4–34.2 %. The content of these elements in breast collection No. 4 was found to be 13.3–920.7 mg/kg, and the degree of extraction the infusion was 3–40 %. Comparative analysis showed that the extraction of B, Al, Ba from the collection into the infusion is 14–58 % higher than from the individual components included in its composition. It has been established that 50 % of boron and 264 % of silicon from the recommended adequate level of consumption in the Russian Federation enters the human body with an infusion from the breast collection No. 4. Conclusion. The study showed that breast collection No. 4 can be considered as an additional source of B and Si in the human body. The concentrations of Al, Sr, Ba, Ti were within the average values of the range of the content of these elements in plants.
《乳房文集》第4号中微量元素的内容
介绍。微量元素是人体的重要组成部分,但大约80%的人注意到其含量不平衡。药用植物含有可获取和可消化的矿物质以及生物活性物质。草药制剂是非常流行的预防和作为各种疾病的复杂治疗的一部分。然而,关于多组分中药制剂中微量元素含量的信息非常有限。因此,有必要研究矿物组成,这将使我们能够考虑将植物收藏作为微量元素的额外来源。的目标。本研究的目的是研究乳腺4号标本中微量元素(B、Si、Al、Ba、Sr、Ti)的含量及其组分和水提物。材料和方法。研究对象为4号乳腺标本、其各组分及其水萃取物。根据药用草药制剂包装上的使用说明从样品中获得输液。在Milestone Ethos Up微波系统(Milestone,意大利)中,用浓硝酸和去离子水的混合物制备样品进行分析。采用电感耦合等离子体原子发射光谱法,在ISP-NPP 720-ES装置(Agilent Technologies, USA)上进行分析。结果和讨论。结果表明,各组分中Si、Al、B、Sr、Ba、Ti的含量在2.9 ~ 1240 mg/kg之间,微量元素向水提物的转移率为0.4 ~ 34.2%。4号乳腺标本中这些元素的含量为13.3 ~ 920.7 mg/kg,输液提取度为3 ~ 40%。对比分析表明,从收集物中提取B、Al、Ba比从其组成中的单个成分中提取高14 - 58%。经证实,在俄罗斯联邦,50%的硼和264%的硅的推荐摄取量是通过乳房收集4号的输注进入人体的。结论。研究表明,4号采乳可以被认为是人体中B和Si的额外来源。Al、Sr、Ba、Ti的含量均在植物中这些元素含量的平均值范围内。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Drug Development and Registration
Drug Development and Registration Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
1.20
自引率
0.00%
发文量
61
审稿时长
8 weeks
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