Preparation of Inorganic Composites of Chitosan/magnesium Oxide Nanoparticle for Antibacterial Activity

Abstract

Natural polymer based nanocomposites have received attention in research due their biocompatible nature and their versatile application in medical field. In the current investigation, we report the synthesize of chitosan /magnesium oxide nanoparticle (CS/MgO) composite material. The prepared sample was characterized by analytical methods such as FTIR, XRD and HRSEM.The antibacterial activity of the CS/MgO composite was evaluated. FT-IR spectral results showed the CS/MgO composite has distinctive functional groups. HR SEM images revealed that the formation of well dispersed MgO nanoparticles in CS and it is observed that the MgO nanoparticles are embedded between the functional moieties present in the chitosan which shows the good interaction between chitosan and MgO nanoparticles. The antibacterial activity of the composite was evaluated against Staphylococcus aureus and Escherichia coli. It is observed that the CS/MgO composite material showed comparatively higher inhibition against E. coli than S.aureus