TREATMENT TACTICS FOR SEVERE REFRACTORY ARTERIAL HYPERTENSION IN AN ADOLESCENT WITH ABDOMINAL AORTIC HYPOPLASIA AND RENAL ARTERY STENOSIS. A CLINICAL CASE

Q4 Medicine
A.E. Matyunova, S.A. Sakhovsky, L.V. Bregel, B.L. Mironkov, I.A. Miloserdov, Yu.A. Kozlov, I.A. Kovalev, T.S. Korinets, A.O. Barakin
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Abstract

Renovascular arterial hypertension (AH) is one of the most common and prognostically most serious secondary hypertensions in children, however, descriptions of renal artery stenosis as part of middle aortic syndrome are quite rarely described Worldwide, and the etiology of this syndrome remains unclear in more than half of all the cases. Treatment approaches include a combination of complex conservative and surgical endovascular techniques that require constant monitoring of effectiveness. A clinical case observation and treatment tactics for refractory hypertension in an adolescent patient with hypoplasia of the abdominal aorta, stenosis of both renal arteries, a progressive decline in the function and volume of the left kidney (a picture of shrinkage of the left kidney on scintigraphy, an increase in hyperazotemia) and left ventricular (LV) hypertrophy is presented. Due to the ineffectiveness of drug antihypertensive therapy, the patient subsequently underwent aortoaortic bypass surgery of the abdominal aorta with prosthetics and implantation of the left renal artery into the shunt, balloon vasodilation with the installation of stents in the lower pole artery of the left kidney and the right renal artery. Over time, there was an improvement in the velocity parameters of the vessels of both kidneys, a decrease in blood pressure to values close to normal and regression of LV hypertrophy. Conclusion: the treatment tactics for a patient with renovascular hypertension and hypoplasia of the abdominal aorta, including drug methods in combination with two-stage surgical correction - the application of an aortoaortic shunt and endovascular treatment - turned out to be the most effective in terms of controlled hypertension.
青少年腹主动脉发育不全合并肾动脉狭窄的严重难治性高血压的治疗策略。1例临床病例
肾血管性动脉高血压(AH)是儿童中最常见和预后最严重的继发性高血压之一,然而,肾动脉狭窄作为中主动脉综合征的一部分的描述在世界范围内很少被描述,并且该综合征的病因在所有病例中有一半以上仍不清楚。治疗方法包括复杂的保守和手术血管内技术的结合,需要持续监测有效性。本文报告1例青少年顽固性高血压患者的临床病例观察及治疗策略,该患者表现为腹主动脉发育不全,双肾动脉狭窄,左肾功能和体积进行性下降(扫描示左肾萎缩,高氮血症增加),左心室肥厚。由于药物降压治疗无效,患者随后行假体腹主动脉搭桥手术,将左肾动脉植入分流管内,左肾下极动脉和右肾动脉球囊血管扩张术,分别安装支架。随着时间的推移,双肾血管流速参数有所改善,血压降至接近正常水平,左室肥厚消退。结论:1例肾血管性高血压合并腹主动脉发育不全患者的治疗策略,包括药物结合两期手术矫正——应用主动脉分流术和血管内治疗——是控制高血压最有效的方法。
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来源期刊
Pediatriya - Zhurnal im G.N. Speranskogo
Pediatriya - Zhurnal im G.N. Speranskogo Medicine-Pediatrics, Perinatology and Child Health
CiteScore
0.60
自引率
0.00%
发文量
150
期刊介绍: Journal “Pediatria” named after G.N. Speransky (the official short names of the Journal are “Journal «Pediatria»,” “Pediatria,” and “«Pediatria,» the Journal”) is the oldest Soviet-and-Russian (in the Russian Federation, the CIS and former Soviet Union) scientific and practical medical periodical assigned for pediatricians that is published continuously since May, 1922, and distributed worldwide. Our mission statement specifies that we aim to the ‘raising the level of skills and education of pediatricians, organizers of children’s health protection services, medicine scientists, lecturers and students of medical institutes for higher education, universities and colleges worldwide with an emphasis on Russian-speaking audience and specific, topical problems of children’s healthcare in Russia, the CIS, Baltic States and former Soviet Union Countries and their determination with the use of the World’s best practices in pediatrics.’ As part of this objective, the Editorial of the Journal «Pediatria» named after G.N. Speransky itself adopts a neutral position on issues treated within the Journal. The Journal serves to further academic discussions of topics, irrespective of their nature - whether religious, racial-, gender-based, environmental, ethical, political or other potentially or topically contentious subjects. The Journal is registered with the ISSN, - the international identifier for serials and other continuing resources, in the electronic and print world: ISSN 0031-403X (Print), and ISSN 1990-2182 (Online). The Journal was founded by the Academician, Dr. Georgiy Nestorovich SPERANSKY, in May, 1922. Now (since 1973) the Journal bears his honorary name.
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