Influence of Antioxidant Correction on Structural and Functional Changes of the Thyroid Gland in Case of Experimental Iodine Deficient Hypothyroidism

Oksana Tuchak, Ihor Luchko, Nadiia Pobigun, Iryna Dubkovetska
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Abstract

Experimental iodine deficient hypothyroidism is manifested by an increase the activity of oxidative processes and a decrease the indicators of antioxidant defense of blood, which is accompanied by the appearance of destructive changes in the tissues of thyroid gland. The comparative analysis of the obtained results confirms the advantage of α-tocopherol using in the complex with potassium iodide for the correction of hypothyroidism, antioxidant imbalance and structural changes of the thyroid gland.
抗氧化校正对实验性缺碘性甲状腺功能减退患者甲状腺结构和功能变化的影响
实验性碘缺乏性甲状腺功能减退症表现为血液氧化过程活性增加,抗氧化防御指标降低,甲状腺组织出现破坏性改变。通过对所得结果的比较分析,证实了α-生育酚与碘化钾配合物在纠正甲状腺功能减退、抗氧化失衡和甲状腺结构改变方面的优势。
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