Prevalence and Predictors of Psychiatric Disorders in Patients with Epilepsy in a Tertiary Level Care Hospital

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Abstract

Background: Common mental disorders are severe and frequent co-morbid psychiatric illnesses with epilepsy.Different study findings across the world showed that patients with epilepsy have a higher burden of mentaldisorders than the general population. However, these issues in patients with epilepsy have been consistentlyundiagnosed.Objectives: The study aimed to screen common mental disorders and the determinants among patients withepilepsy.Methods: An institutional-based cross-sectional study was conducted among patients with Epilepsy from March10 to May 15, 2021. Patients were assessed for the risk of common mental disorders using a pretested, structured,self-reporting questionnaire (SRQ-20). The collected data were entered into Epi-data version 3.1 software andanalyzed using R version 4.0 software. Descriptive statistics were computed using frequency, percent, mean,and standard deviations. A simple logistic regression model was fit to identify the association and strength ofexploratory variables and common mental disorders at a 95% confidence interval and p-value < 0.05.Results: The study included 202 patients diagnosed with epilepsy and yielded a response of 91.4%. About 53%of the patients were males. The magnitude of common mental disorders among patients with epilepsy was 57.9%(95% CI: 44.56, 71.24). Being more than one substance user (AOR = 5.7; 95%CI: 1.6, 20.7) and Not having socialsupport (AOR = 4.3; 95%CI: 1.5, 11.9) were the identified determinants of common mental disorders.Conclusion: The magnitude of common mental disorders among patients with epilepsy were high. Not havingsocial support and khat chewing were the identified risk factors significantly associated with common mentaldisorders. Early screening and treatments are the key interventions to prevent complications and deaths fromcommon mental disorders.
三级医院癫痫患者精神障碍患病率及预测因素
背景:常见精神障碍是严重且常与癫痫共病的精神疾病。世界各地不同的研究结果表明,癫痫患者的精神障碍负担高于一般人群。然而,癫痫患者的这些问题一直没有得到诊断。目的:筛选癫痫患者常见的精神障碍及其影响因素。方法:于2021年3月10日至5月15日对癫痫患者进行基于机构的横断面研究。采用预先测试的结构化自我报告问卷(SRQ-20)评估患者常见精神障碍的风险。收集的数据输入Epi-data 3.1版软件,使用R 4.0版软件进行分析。描述性统计使用频率、百分比、平均值和标准差计算。采用简单的logistic回归模型,在95%的置信区间和p值<0.05.结果:该研究纳入202例癫痫患者,有效率为91.4%。约53%的患者为男性。癫痫患者常见精神障碍程度为57.9%(95% CI: 44.56, 71.24)。一个以上物质使用者(AOR = 5.7;95%CI: 1.6, 20.7)和无社会支持(AOR = 4.3;95%CI: 1.5, 11.9)是常见精神障碍的确定因素。结论:癫痫患者常见精神障碍程度较高。缺乏社会支持和嚼阿拉伯茶是与常见精神障碍显著相关的风险因素。早期筛查和治疗是预防常见精神障碍并发症和死亡的关键干预措施。
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