Variation of PAI-1 and oxidant-antioxidant status in Four Human Cancers

Zahraa Hayder Razzaq Al_Ali, None Elham Abed Mahdi
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Abstract

Objective: The present study was disigned to invistigate the effect of plasmin-plasminogen system variable which is plasminogen activator inhibitor-1 (PAI-1) on the occurrence of the development of malignant and benign tumors. In addition to illustrate the oxidative stress effect on the malignant and benign tumors occuring and complication progress. Which involving Glutathione Peroxidase (GPx) and Hydrogen Peroxide H2O2. On the other hand, current study amied to nominate the most suitable variant as an effective tumor marker
四种人类癌症中PAI-1和氧化-抗氧化状态的变化
目的:探讨纤溶酶原系统变量纤溶酶原激活物抑制剂-1 (PAI-1)在恶性肿瘤和良性肿瘤发生发展中的作用。此外还阐述了氧化应激对恶性肿瘤和良性肿瘤发生及并发症进展的影响。其中涉及谷胱甘肽过氧化物酶(GPx)和过氧化氢H2O2。另一方面,目前的研究尚未确定最合适的变异作为有效的肿瘤标志物
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