ENTENDENDO OS PRINCIPAIS DÉFICITS DE MEMÓRIA NA FASE INICIAL DA DOENÇA DE ALZHEIMER

Abstract

This work aims to present an understanding of the main memory deficits in the early stages of Alzheimer's disease. For this, a bibliographical research was carried out in the Google Scholar database with keywords such as "early stage of Alzheimer's disease", "semantic memory" and "episodic memory". We explored the complexity of the disease, characterized by neurodegeneration and brain atrophy, with memory loss as a prominent symptom. We analyzed the phases of the disease, focusing on the initial phase subdivided into three stages. We detail each stage, highlighting its characteristics. We address biological changes, including the formation of senile plaques and neurofibrillary tangles, which disrupt synapses and affect communication between neurons. In the section on memory, we identify the affected types, mainly episodic and semantic memory, highlighting their importance in the early stages. We explore the relationship between biological changes and memory deficits. We conclude by emphasizing the complexity of the disease, the need for continuous research and the importance of early diagnosis. We discuss challenges in formulating universal treatments due to individual variation and societal changes. We highlight the urgency of future research to face the challenges of this devastating disease.