Differences in the Effect of Giving Fe Tablets and Capsules Moringa Leaves on Hepcidin and Ferritin Levels in Anemic Pregnancy Rats

IF 0.2 0 HUMANITIES, MULTIDISCIPLINARY

Contagion-Journal of Violence Mimesis and Culture Pub Date : 2023-09-01 DOI:10.30829/contagion.v5i3.17395

Novita Sari, Delmi Sulastri, Endrinaldi Endrinaldi

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Abstract

Anemia is a condition characterized by a decrease in Hemoglobin (HB), a serious global public health problem especially affecting children and pregnant women. This study aimed to determine differences in the effect of giving Fe tablets and capsules of Moringa leaves on hepcidin and ferritin levels in anaemic pregnancy rats. This research was an experimental study with a randomized post-test-only control group design. This research was conducted at the Animal House of the Faculty of Medicine, Andalas University to maintain and treat experimental animals. Ferritin and Hepcidin examinations were carried out at the biomedical laboratory of the Faculty of Medicine, Andalas University. The sample in this study were female white rats (Rattus Novergicus) which met the inclusion and exclusion criteria, the data were analyzed using One Way Anova. The results of this study indicated that the mean hepcidin levels in the Fe (P1) and Moringa leaf capsule (P2) groups were 181.902 ± 20.31 and 216.362 ± 29.90 with a p-value of 0.006 . The mean ferritin levels in the Fe(P1) and Moringa leaf capsule (P2) groups were 1.928 ± 0.263 and 2.308 ± 0.320 with a p-value of 0.004. The conclusion in this study was that there was an effect on hepcidin levels after being given Fe tablets (P1) and Moringa leaf capsules (P2) to anemic pregnant rats and there was an effect on ferritin levels after being given Fe tablets (P1) and Moringa leaf capsules (P2) to anemic pregnant rats

Keyword: Anemic, Ferritin, Fe Tablets, Hepcidin, Moringa Leaf Capsules

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给予辣木叶铁片和铁胶囊对贫血妊娠大鼠Hepcidin和铁蛋白水平影响的差异

贫血是一种以血红蛋白(HB)减少为特征的疾病，是一个严重的全球公共卫生问题，尤其影响到儿童和孕妇。本研究旨在确定辣木叶和辣木叶分别给予辣木叶和辣木叶分别给予辣木叶和辣木叶分别给予辣木叶和辣木叶分别给予辣木叶和辣木叶分别给予辣木叶和辣木叶分别给予辣木叶和辣木叶分别给予辣木叶和辣木叶。on & lt; em>& lt; / em> & lt; em> hepcidin & lt; / em> & lt; em>和铁蛋白& lt; / em> & lt; em> level & lt; em> s & lt; / em> & lt; em>贫血pregnan & lt; em> cy & lt; em>老鼠。本研究是一项实验研究，采用随机后验对照组设计。本研究在安达拉斯大学医学院动物馆进行，以维持和治疗实验动物。铁蛋白和Hepcidin检查在安达拉斯大学医学院生物医学实验室进行。本研究样本为雌性白鼠(Rattus Novergicus)，符合纳入和排除标准，数据采用单因素方差分析(One Way Anova)。结果表明，铁(P1)组和辣木叶胶囊(P2)组hepcidin的平均水平分别为181.902±20.31和216.362±29.90,p值为0.006。铁(P1)组和辣木叶胶囊(P2)组的平均铁蛋白水平分别为1.928±0.263和2.308±0.320,p值为0.004。本研究的结论是:妊娠贫血大鼠给予铁片(P1)和辣木叶胶囊(P2)对hepcidin水平有影响，妊娠贫血大鼠给予铁片(P1)和辣木叶胶囊(P2)对铁蛋白水平有影响。关键词:贫血;铁蛋白;铁片;Hepcidin;辣木叶胶囊;/em></strong;

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来源期刊

Contagion-Journal of Violence Mimesis and Culture HUMANITIES, MULTIDISCIPLINARY-

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0.10

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0.00%

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