Genetic Polymorphisms Involved in Bladder Cancer: A Global Review

IF 3.1 Q2 ONCOLOGY

Oncology Reviews Pub Date : 2023-11-06 DOI:10.3389/or.2023.10603

Hampig Raphael Kourie, Joseph Zouein, Bahaa Succar, Avedis Mardirossian, Nizar Ahmadieh, Eliane Chouery, Cybel Mehawej, Nadine Jalkh, Joseph kattan, Elie Nemr

引用次数: 0

Abstract

Bladder cancer (BC) has been associated with genetic susceptibility. Single peptide polymorphisms (SNPs) can modulate BC susceptibility. A literature search was performed covering the period between January 2000 and October 2020. Overall, 334 articles were selected, reporting 455 SNPs located in 244 genes. The selected 455 SNPs were further investigated. All SNPs that were associated with smoking and environmental exposure were excluded from this study. A total of 197 genes and 343 SNPs were found to be associated with BC, among which 177 genes and 291 SNPs had congruent results across all available studies. These genes and SNPs were classified into eight different categories according to their function.

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膀胱癌基因多态性研究综述

膀胱癌(BC)与遗传易感性有关。单肽多态性(snp)可以调节BC的易感性。检索了2000年1月至2020年10月期间的文献。总共有334篇文章被选中，报告了244个基因中的455个snp。选取的455个snp进行进一步研究。所有与吸烟和环境暴露相关的snp都被排除在本研究之外。共发现197个基因和343个snp与BC相关，其中177个基因和291个snp在所有现有研究中结果一致。这些基因和snp根据其功能被分为8个不同的类别。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oncology Reviews ONCOLOGY-

CiteScore

6.30

自引率

0.00%

发文量

审稿时长

9 weeks

期刊介绍： Oncology Reviews is a quarterly peer-reviewed, international journal that publishes authoritative state-of-the-art reviews on preclinical and clinical aspects of oncology. The journal will provide up-to-date information on the latest achievements in different fields of oncology for both practising clinicians and basic researchers. Oncology Reviews aims at being international in scope and readership, as reflected also by its Editorial Board, gathering the world leading experts in both pre-clinical research and everyday clinical practice. The journal is open for publication of supplements, monothematic issues and for publishing abstracts of scientific meetings; conditions can be obtained from the Editor-in-Chief or the publisher.