Phyto-Pharmacological Investigation of Ethanolic Extract of Flowers of Bauhinia acuminata

Abstract

Bauhinia acuminata is a type of angiosperm in the Fabaceae family, native to South and Southeast Asia, South China, Burma, India, Nepal, Pakistan, and Sri Lanka. The common names include B. acuminata, mountain ebony, camel’s foot tree, kachnar, and butterfly ash. Angiosperm tree could be widely used as a medicinal plant common in tropical regions. Flowers, buds, stems, roots, bark, seeds, and leaves have been used to treat many ailments since ancient times. NSAIDs are one of the most important classes of drugs used today, and several clinical problems require long-term use. As a result of long-term use, side effects, especially stomach ulcers, can worsen the patient’s clinical symptoms. So there is a requirement to go for painkillers, but it is not related to problems even with chronic use. The literature says that a lot of analytical work has been done on this plant, but none of it has been evaluated for its analgesic and anti-inflammatory effects. An aqueous ethanolic extract was prepared and its analgesic, anti-inflammatory, and antipyretic effects were evaluated in animal models. The results showed that the flower extract at 200 mg/kg dose had significant analgesic, anti-inflammatory, and antipyretic effects compared to the medicinal active drugs.