Evaluating the dynamics of hospital COVID-19 contacts and subsequent conversion to SARS-CoV-2 infection: a multi-centre retrospective cohort study

IF 1.8 Q3 INFECTIOUS DISEASES
Nneoma Okeke , Luke B. Snell , Balram Rathish , Amal Hussein , William Newsholme , Damien Mack , Aodhan Breathnach , Jonathan A. Otter
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引用次数: 0

Abstract

We investigated the dynamics of COVID-19 contacts subsequent conversion to SARS-CoV-2 infection in an inpatient setting across three National Health Service (NHS) Trusts. 9.2% (476/5,156) COVID-19 contacts met inclusion criteria, were typable and tested positive for COVID-19. There was no significant difference between Omicron and non-Omicron contacts overall conversion proportions. Omicron contacts converted faster than non-Omicron contacts (median 3 days vs 4 days, P=0.03), and had significantly greater proportions of early conversions at day 3, 5, and 7 timepoints.

评估医院 COVID-19 接触者及其后转为 SARS-CoV-2 感染的动态:一项多中心回顾性队列研究
我们调查了三个国民健康服务(NHS)托管医院住院病人中 COVID-19 接触者随后转为 SARS-CoV-2 感染的动态。9.2%(476/5,156)的 COVID-19 接触者符合纳入标准,可进行分型,且 COVID-19 检测呈阳性。欧米克隆和非欧米克隆接触者的总体转化比例没有明显差异。欧米克隆接触者的转化速度快于非欧米克隆接触者(中位数为 3 天 vs 4 天,P=0.03),而且在第 3、5 和 7 天时间点的早期转化比例明显更高。
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来源期刊
Infection Prevention in Practice
Infection Prevention in Practice Medicine-Public Health, Environmental and Occupational Health
CiteScore
4.80
自引率
0.00%
发文量
58
审稿时长
61 days
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