ACOMPARATIVE STUDY OF ANTIMICROBIAL ACTIVITY OF MELALEUCA ALTERNIFOLIA,ACHILLEA MILLEFOLIUMAND CINNNAMOMUM CAMPHORAVAGINAL SUPPOSITORIES

IF 1.3 Q2 AGRICULTURE, MULTIDISCIPLINARY

Acta Technologica Agriculturae Pub Date : 2023-10-01 DOI:10.51558/2232-7568.2023.16.1.1

Merima Ibišević, Saša Pilipović, Darja Husejnagić, Fadila Malohodžić, Alma Kulanić, Lejla Mustafić, Ermina Cilović Kozarević, Emir Horozić, Enida Karić

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引用次数: 0

Abstract

Vaginal inflammation represents a heterogeneous group of disorders caused by infection, inflammation, or disruption of vaginal microflora. The most common causes of vaginal infection are Staphylococcus aureus, Enterococcus faecalis, Streptococcus agalactiae, Escherichia coliand Candida albicans. Antibiotic resistance is a major global problem, which can be mitigated by using natural antimicrobial substances such as essential oils. Each essential oil has an extremely complex composition (some essential oilshave over 200 components), which prevents microorganisms from developing resistance. Therefore, essential oils retain their effects.The aim of our study was to investigate antibacterial activity Melaleuca alternifolia, Achillea millefoliumand Cinnamomumcamphoravaginal suppositories, and see which essential oil has the strongest potential to be used as active ingredient for vaginal infections.The antimicrobial activity of the vaginal suppositories was examined using the disk diffusion method. Standard bacterial strains were used for the ATCC collection: Staphylococcus aureus (S. aureus) ATCC 25923, Enterococcus faecalis (E. faecalis)ATCC 51299, Escherichia coli (E. coli)ATCC 25922, Candida albicans (C. albicans)ATCC 10231.The results showed that Melaleuca alternifolia essential oil has an antimicrobial effect on all tested strains, with the strongest effect on Candida albicans(ZI 22.7 mm). Achillea millefoliumessential oil had no effect on Enterococcus faecalis, whereas Cinnamomum camphoraessential oil did not show zones of inhibition of Candida albicans.KEYWORDS:vaginal suppository, Melaleuca alternifolia, Achillea millefolium, Cinnamomum camphora,antimicrobial activity

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互花千层、千叶阿喀琉木和樟脑阴道栓剂抑菌活性的比较研究

阴道炎症是由感染、炎症或阴道菌群破坏引起的一组异质性疾病。阴道感染最常见的原因是金黄色葡萄球菌、粪肠球菌、无乳链球菌、大肠杆菌和白色念珠菌。抗生素耐药性是一个重大的全球性问题，可通过使用精油等天然抗微生物物质加以缓解。每种精油都有非常复杂的成分(有些精油含有超过200种成分)，这可以防止微生物产生抗药性。因此，精油保留了它们的效果。本研究的目的是研究互花千层、千叶阿喀那和樟脑阴道栓剂的抗菌活性，并观察哪种精油最有可能作为阴道感染的有效成分。采用纸片扩散法检测阴道栓剂的抑菌活性。ATCC采集采用标准菌株:金黄色葡萄球菌(S. aureus) ATCC 25923、粪肠球菌(E. faecalis)ATCC 51299、大肠杆菌(E. coli)ATCC 25922、白色念珠菌(C. albicans)ATCC 10231。结果表明，互花千层精油对所有菌株均有抑菌作用，其中对白色念珠菌(ZI 22.7 mm)抑菌效果最强。千叶阿喀琉叶精油对粪肠球菌无抑制作用，樟树精油对白色念珠菌无抑制作用。关键词:阴道栓剂，互花千层，千叶，樟树，抗菌活性

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来源期刊

Acta Technologica Agriculturae AGRICULTURE, MULTIDISCIPLINARY-

CiteScore

2.50

自引率

28.60%

发文量

审稿时长

18 weeks

期刊介绍： Acta Technologica Agriculturae is an international scientific double-blind peer reviewed journal focused on agricultural engineering. The journal is multidisciplinary and publishes original research and review papers in engineering, agricultural and biological sciences, and materials science. Aims and Scope Areas of interest include but are not limited to: agricultural and biosystems engineering; machines and mechanization of agricultural production; information and electrical technologies; agro-product and food processing engineering; physical, chemical and biological changes in the soil caused by tillage and field traffic, soil working machinery and terramechanics; renewable energy sources and bioenergy; rural buildings; related issues from applied physics and chemistry, ecology, economy and energy.