A review with updated perspectives on in vitro and in vivo wound healing models

IF 1.1 4区 生物学 Q3 BIOLOGY
MURNI NAZIRA SARIAN, NABILAH ZULKEFLI, SHAZELI ZAIN, SANDRA MANIAM, SHARIDA FAKURAZI
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引用次数: 0

Abstract

A skin wound or perforation triggers a series of homeostatic reactions to safeguard internal organs from invasion by pathogens or other substances that could damage body tissues. An injury may occasionally heal quickly, leading to the closure of the skin's structure. Healing from chronic wounds takes a long time. Although many treatment options are available to manage wound healing, an unmet therapy need remains because of the complexity of the processes and the other factors involved. It is crucial to conduct consistent research on novel therapeutic approaches to find an effective healing agent. Therefore, this work aims to cover various in vitro and in vivo methodologies that could be utilised to examine wound recovery. Before deciding on the optimal course of action, several techniques' benefits, drawbacks, and factors need to be reviewed
体外和体内伤口愈合模型的最新观点综述
皮肤伤口或穿孔会引发一系列的体内平衡反应,以保护内部器官免受病原体或其他可能损害身体组织的物质的入侵。伤口有时会很快愈合,导致皮肤结构闭合。慢性伤口的愈合需要很长时间。虽然有许多治疗方案可用于管理伤口愈合,但由于治疗过程的复杂性和其他相关因素,仍然存在未满足的治疗需求。对新的治疗方法进行持续的研究以寻找有效的愈合剂是至关重要的。因此,这项工作旨在涵盖各种体外和体内的方法,可用于检查伤口恢复。在决定最佳行动方案之前,需要审查几种技术的优点、缺点和因素
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来源期刊
CiteScore
4.60
自引率
0.00%
发文量
20
审稿时长
6-12 weeks
期刊介绍: The Turkish Journal of Biology is published electronically 6 times a year by the Scientific and Technological Research Council of Turkey (TÜBİTAK) and accepts English-language manuscripts concerning all kinds of biological processes including biochemistry and biosynthesis, physiology and metabolism, molecular genetics, molecular biology, genomics, proteomics, molecular farming, biotechnology/genetic transformation, nanobiotechnology, bioinformatics and systems biology, cell and developmental biology, stem cell biology, and reproductive biology. Contribution is open to researchers of all nationalities.
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