Incidence of neurological complication symptoms post-mRNA vaccination among the urban population of Makkah Province of Kingdom of Saudi Arabia

Abstract

Objective

This research aimed to assess the incidence of neurological complication symptoms among residents of the Makkah province in Saudi Arabia following the rapid approval and administration of mRNA vaccines. Given the differences in demographic factors such as age, race, medical history, and lifestyle among individuals, close monitoring of vaccine-related side effects becomes crucial, especially in mass vaccination campaigns.

Method

A cross-sectional online survey study was conducted in both English and Arabic languages, with a sample size determined using the Raosoft sample size calculator statistical analyzer. The study aimed for a 95% confidence level, a 5% margin of error, and a response distribution of 50%. Descriptive statistics were employed using Statistical Package for Social Sciences version 22.0. The Shapiro–Wilk test was utilized to assess data normality, and the statistical significance of the data was determined using Pearson's Chi-Squared test and the Kruskal–Wallis test.

Result

The study included 846 volunteers aged 18 and above, all of whom had received mRNA vaccine in the Makkah region. Data were systematically tabulated and categorized for descriptive analysis. The study found P-values less than .05, and the summarized P-values were presented. The majority of participants (73%) were from the Taif area (32%) within the Makkah region.

Conclusion

This study sheds light on the challenges faced by the population of the Makkah region in Saudi Arabia following mRNA vaccinations. Although some complications were reported post-vaccination, it is noteworthy that these challenges were effectively managed by the medical authorities.