The relationship of central macular thickness with clinical grades of diabetic retinopathy

Manoj Tyagi, Shivani Gupta, Mukesh Singh Rajpoot, Shweta Aloney, Pritee Chouhan
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Abstract

To assess central macular thickness (CMT) in diabetics with or without diabetic retinopathy (DR) and compare it with various clinical grades of DR. All patients attending the ophthalmic OPD fulfilling the inclusion and met no exclusion criteria were enrolled in this study. All eyes underwent comprehensive and standardized ophthalmic examination. The CMT was measured using spectral domain optical coherence tomography using Cirrus HD OCT Model 500. The mean CMT in cases is significantly greater than controls. It is also significantly greater in diabetics with DR as compared to diabetics without DR and it significantly varies with various grades of DR. The mean CMT is also increased in patients with diabetic macular edema (DME) and panretinal photocoagulation (PRP) untreated DR as compared to diabetics without DME and PRP treated DR respectively. Central macular thickness can be used as an indicator to monitor individuals with diabetes as it increased in diabetics and the presence of macular edema decreased in PRP treated eyes. It also varies with various grades of DR.
中央黄斑厚度与糖尿病视网膜病变临床分级的关系
为了评估伴有或不伴有糖尿病视网膜病变(DR)的糖尿病患者的中央黄斑厚度(CMT),并将其与不同临床级别的DR进行比较。所有符合纳入标准且不符合排除标准的眼科OPD患者均被纳入本研究。所有眼均行全面规范的眼科检查。CMT测量使用光谱域光学相干断层扫描,使用Cirrus HD OCT Model 500。病例的平均CMT明显大于对照组。伴有糖尿病性黄斑水肿(DME)和全视网膜光凝(PRP)治疗的糖尿病患者的平均CMT也分别高于不伴有糖尿病性黄斑水肿(DME)和PRP治疗的糖尿病患者。黄斑中央厚度可以作为监测糖尿病患者的指标,因为糖尿病患者黄斑中央厚度增加,而PRP治疗后黄斑水肿减少。它也随DR的不同等级而不同。
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