A Review on Probiotic and Microbiota Modulation: A Promising Nutraceutical in the Management of Neurodegenerative and Psychiatric Conditions

Abstract

Microbes as probiotics were found to provide the host with health benefits when given in proper doses. Researches are going on to analyze the positive relation of probiotics on digestive health including the changes in the microbial populations in the gut. The immune, nervous, and endocrine system are some of the locations outside of the gut that is affected by probiotics. The study focussed on the potential impact of the “microbiota-gut-brain axis” on CNS-related functions. The role of probiotics is highlighted in our study for the control of a number of CNS illnesses, including Alzheimer’s disease, anxiety, obsessive-compulsive disorder, etc. This review also provides an overview of some clinically proven commercial probiotics and clinical studies reporting the impact of probiotics augmentation in cognition and symptoms in individuals with severe neurological and psychiatric illnesses.