Clinical case of successful application of photodynamic therapy in advanced vulvar cancer

Q3 Medicine

Biomedical Photonics Pub Date : 2023-10-23 DOI:10.24931/2413-9432-2023-12-3-21-24

N. A. Shanazarov, T. G. Grishachevа, G. S. Aldabergen, S. B. Smailova, Zh. Zh. Salmaganbetova

引用次数: 0

Abstract

A significant therapeutic effect of photodynamic therapy (PDT) is shown in a patient with extensive vulvar cancer after ineffective surgical and chemoradiotherapy. During the year, three courses of local PDT with a photosensitizer based on chlorin e6 were carried out. The photosensitizer was administered intravenously three hours before irradiation at a dose of 1.2 mg/kg. For laser irradiation (662 nm) of the vulvar tumor, a light guide for external irradiation was used: the power density was 0.2 W/cm 2 , the light dose was from 100 to 250 J/cm 2 . As a result of treatment, tumor regression and stable remission are observed. The patient remains under observation.

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光动力疗法在晚期外阴癌中的成功应用

光动力疗法(PDT)对一例手术和放化疗无效的广泛性外阴癌患者的治疗效果显著。年内，进行了三个疗程的本地PDT，使用基于氯e6的光敏剂。光敏剂在照射前3小时静脉注射，剂量为1.2 mg/kg。外阴肿瘤激光照射(662 nm)采用外照射光导，功率密度为0.2 W/cm 2，光剂量为100 ~ 250 J/cm 2。治疗后，观察到肿瘤消退和稳定缓解。病人仍在观察中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biomedical Photonics Medicine-Surgery

CiteScore

1.80

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The main goal of the journal – to promote the development of Russian biomedical photonics and implementation of its advances into medical practice. The primary objectives: - Presentation of up-to-date results of scientific and in research and scientific and practical (clinical and experimental) activity in the field of biomedical photonics. - Development of united Russian media for integration of knowledge and experience of scientists and practitioners in this field. - Distribution of best practices in laser medicine to regions. - Keeping the clinicians informed about new methods and devices for laser medicine - Approval of investigations of Ph.D candidates and applicants.