Antimicrobial properties of ethanolic plant extracts on microorganisms of the genus Staphylococcus aureus, Echerihia coli

Abstract

Nowadays, the importance of medicinal plants has increased significantly as a source of biologically active substances, including antibacterial action. There is an intensive search for effective and safe drugs that could perform the function of preventive disinfection, reduce the negative impact on the animal's body and the environment as a whole, and be economically beneficial. Therefore, we chose 17 promising types of plant raw materials for the study due to the sufficient prevalence and diversity of chemical composition. The scientific work presents the results of the effectiveness of ethanolic plant extracts against aureus, Echerihia coli and Staphylococcus. The antibacterial effect of plant tinctures of Kalgan, Comfrey, Bearberry, Geranium, Nut membranes and Dandelion on St. Aureus strain 209 P and E. coli strain 1257 was revealed. According to the results of the studies, high and moderate antibacterial activity of plant materials was found, which is an effective means of preventive measures in veterinary medicine. It has also been found that the “wells” method is more effective than the paper disc method and gives a more accurate result, so it is relevant in further research. Herbal medicines account for more than 50 % of all pharmaceuticals. A significant place among them is occupied by prophylactic disinfectants used to prevent diseases. The main active substances of such products are secondary metabolites of medicinal plants, which include phenols and flavonoids, that in turn have antimicrobial effects. The content of these substances is controlled by analyzing extracts made from plant material. Calgan is a perennial medicinal plant of the Pink family that has a number of powerful properties. The rhizome of this plant contains flavonoids, wax, iron, starch, malic acid, essential oils, catechin, glycosides, vitamins PP, A, Z. Comfrey is a perennial herbaceous plant that belongs to the family of broadleaves. The highest concentration of nutrients is found in the rhizome of the three-year-old plant: tannins, amino acids, alkaloids, flavonoids, etc. Geranium is a perennial herb of the geranium family, rich in tannins – tannins are found in the rhizome and ground part of the plant. It also contains flavonoids, triterpene saponins, carotene, vitamin C, and starch. Dandelion is a perennial plant from the aster family. The roots contain inulin, fructose, organic acids, steroids, flavonoids, tannins, waxes, and higher fatty acids. The walnut membranes are rich in iodine, zinc, magnesium, ascorbic and nicotinic acids, PP and B vitamins, tannins, and essential oils. Bearberry is a genus of evergreen hardwood shrubs of the heather family. The main active ingredients are phenolic compounds.